{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T15:01:32Z","timestamp":1775919692340,"version":"3.50.1"},"reference-count":21,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,5,6]],"date-time":"2016-05-06T00:00:00Z","timestamp":1462492800000},"content-version":"vor","delay-in-days":11358,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[1985,4]]},"abstract":"<jats:p>Since its introduction in 1981 uvulopalatopharyngoplasty (UPPP) has become an alternative surgical approach to permanent tracheostomy in treating obstructive sleep apnea (OSA). However, the criteria for selecting candidates for this procedure are unclear and the prediction of a positive response remains an enigma. This article presents the experience with UPPPs performed on 35 patients who had moderate to severe OSA. Criteria for patient selection included apnea severity, cardiopulmonary sequelae, and clinical symptomatology. All but two patients demonstrated clinical improvement, although there was considerable variability in the degree of response. Patients were classified as good or poor responders on the basis of the severity index (SI), which represents the number of apneas and hypopneas per hour of sleep resulting in oxygen saturation below 85%. A greater than 50% improvement in the SI was considered a good response. Twenty\u2010three patients (65.7%) were good responders and the remaining 12 (34.3%) were poor responders. The need for permanent tracheostomy was obviated In 16 of 32 patients presenting with disabling daytime sleepiness or severe cardiopulmonary sequelae. Therefore it appears that UPPP is useful for treating most OSA patients.<\/jats:p>","DOI":"10.1177\/019459988509300223","type":"journal-article","created":{"date-parts":[[2017,1,26]],"date-time":"2017-01-26T23:52:55Z","timestamp":1485474775000},"page":"244-250","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":62,"title":["Further Evaluation of Uvulopalatopharyngoplasty in the Treatment of Obstructive Sleep Apnea Syndrome"],"prefix":"10.1002","volume":"93","author":[{"given":"George P.","family":"Katsantonis","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery St. Louis University School of Medicine St. Louis Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James K.","family":"Walsh","sequence":"additional","affiliation":[{"name":"Sleep Disorders Center Deaconess Hospital St. Louis Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paula K.","family":"Schweitzer","sequence":"additional","affiliation":[{"name":"Sleep Disorders Center Deaconess Hospital St. Louis Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William H.","family":"Friedman","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery St. Louis University School of Medicine St. Louis Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,5,6]]},"reference":[{"key":"e_1_2_1_2_1","volume-title":"The sleep apnea syndromes","author":"Guilleminault C","year":"1978"},{"key":"e_1_2_1_3_1","first-page":"568","article-title":"Etude polygraphique des manifestations \u00e9pisodeques (Hypniques et respiratoires) diurnes et nocturnes, du syndrome de Pickwick","volume":"112","author":"Gastaut H","year":"1965","journal-title":"Rev Neurol 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