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The irradiation\u2010failure group showed a significantly greater invasion of cartilage and extension into subglottic areas. The extension of tumors along blood vessels and mucous glands appeared to contribute to the spread of tumors in the irradiation\u2010failure group. These findings have implications for the surgical management of irradiation failures in the treatment of laryngeal cancers.<\/jats:p>","DOI":"10.1177\/019459988609500215","type":"journal-article","created":{"date-parts":[[2015,11,25]],"date-time":"2015-11-25T07:03:58Z","timestamp":1448435038000},"page":"213-218","source":"Crossref","is-referenced-by-count":36,"title":["Coronal Sections of Larynges from Radiationtherapy Failures: A Clinical\u2010Pathologic Study"],"prefix":"10.1002","volume":"95","author":[{"given":"James H.","family":"Brandenburg","sequence":"first","affiliation":[{"name":"Division of Otolaryngology\u2014Head and Neck Surgery University of Wisconsin\u2010Madison Madison Wisconsin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth G.","family":"Condon","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology\u2014Head and Neck Surgery University of Wisconsin\u2010Madison Madison Wisconsin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Terrence W.","family":"Frank","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology\u2014Head and Neck Surgery University of Wisconsin\u2010Madison Madison Wisconsin"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1986,9]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-197704000-00002"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348947108000503"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1972.00770080787002"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348946807700602"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348946907800402"},{"key":"e_1_2_1_7_1","volume-title":"Cancer of the head and neck","author":"MacComb WS","year":"1967"},{"key":"e_1_2_1_8_1","first-page":"1","article-title":"Growth and spread of laryngeal and hypopharyngeal carcinomas with reflections on the effect of preoperative irradiation: 139 cases studied by whole organ serial sections","volume":"308","author":"Olofasson J","year":"1973","journal-title":"Acta Otolaryngol"},{"issue":"4","key":"e_1_2_1_9_1","first-page":"507","article-title":"Mucous gland involvement in cancer at the anterior commissure","volume":"3","author":"Bridger GP","year":"1974","journal-title":"Can J Otolaryngol"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.2890050507"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348946107000321"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-197503000-00009"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/019459988609500215","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/019459988609500215","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T14:23:42Z","timestamp":1760970222000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1177\/019459988609500215"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,9]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1986,9]]}},"alternative-id":["10.1177\/019459988609500215"],"URL":"https:\/\/doi.org\/10.1177\/019459988609500215","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"value":"0194-5998","type":"print"},{"value":"1097-6817","type":"electronic"}],"subject":[],"published":{"date-parts":[[1986,9]]}}}