{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T16:09:28Z","timestamp":1761581368492,"version":"build-2065373602"},"reference-count":14,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[1987,11,1]],"date-time":"1987-11-01T00:00:00Z","timestamp":562723200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[1987,11]]},"abstract":"<jats:p>It has been suggested by numerous researchers that the development of conditioned food aversion (CFA) in experimental animals represents the presence of a subjective state of illness. Squirrel monkeys with proven susceptibility to rotation\u2010induced vomiting were given surgical bilateral labyrinthectomies, a procedure known to abolish signs and symptoms of motion sickness in human beings. Postoperatively, labyrinthectomized monkeys neither vomited nor revealed any reduction in food consumption when exposed to provocative rotation. Other samples of monkeys known to be refractory to horizontal rotation and to sinusoidal vertical motion also exhibited little tendency to acquire a conditioned aversion to banana. But monkeys who had sham operations and those who revealed weak\u2010to\u2010strong signs of motion sickness exhibited a marked CFA (significant reduction in food intake). The strength of CFA was much greater when elicited in the test vehicle when compared with response in the home cage. The findings are interpreted as support for a limited application of CFA procedures for inferring the presence of motion\u2010induced nausea and malaise.<\/jats:p>","DOI":"10.1177\/019459988709700501","type":"journal-article","created":{"date-parts":[[2015,11,25]],"date-time":"2015-11-25T07:07:24Z","timestamp":1448435244000},"page":"433-440","source":"Crossref","is-referenced-by-count":9,"title":["Subjective Concomitants of Motion Sickness: Quantifying Rotation\u2010induced Illness in Squirrel Monkeys"],"prefix":"10.1002","volume":"97","author":[{"given":"Chester R.","family":"Wilpizeski","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Thomas Jefferson University Medical College Philadelphia Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louis D.","family":"Lowry","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Thomas Jefferson University Medical College Philadelphia Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven J.","family":"Green","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Thomas Jefferson University Medical College Philadelphia Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"B. Davison","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Thomas Jefferson University Medical College Philadelphia Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Howard","family":"Melnick","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Thomas Jefferson University Medical College Philadelphia Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1987,11]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"702","article-title":"Appareil pour l'\u00e9tude de l'influence des oscillations rhythmique sur les animaux de laboratoire","volume":"85","author":"Pozerski E","year":"1921","journal-title":"Compt Rend Soc Biol"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1139\/cjr45e-023"},{"key":"e_1_2_1_4_1","first-page":"215","article-title":"Motion sickness in the squirrel monkey","volume":"51","author":"Ordy JM","year":"1980","journal-title":"Aviat Space Environ Med"},{"key":"e_1_2_1_5_1","first-page":"S91","article-title":"The chemoreceptor trigger zone for vomiting is not essential for motion sickness in cats","volume":"27","author":"Borison HL","year":"1984","journal-title":"Physiologist"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/019459988609400517"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1964.00750030188016"},{"key":"e_1_2_1_8_1","first-page":"614","article-title":"Motion sickness in cats: a symptom\u2010rating scale used in laboratory and flight tests","volume":"50","author":"Suri KB","year":"1979","journal-title":"Aviat Space Environ Med"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016488309130935"},{"key":"e_1_2_1_10_1","first-page":"571","article-title":"Observations of canal sickness and adaptation in chimpanzees and squirrel monkeys in a \u201cslow rotation room.\u201d","volume":"33","author":"Meek JC","year":"1962","journal-title":"Aerospace Med"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0709(85)80002-8"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0163-1047(83)90414-4"},{"key":"e_1_2_1_13_1","first-page":"S61","article-title":"Animal models in motion sickness: are nonemetic species an appropriate choice?","volume":"28","author":"Ossenkopp K\u2010P","year":"1985","journal-title":"Physiologist"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/0031-9384(79)90120-3"},{"volume-title":"Experimental assessments and clinical applications of conditioned food aversions","year":"1985","author":"Braveman NS","key":"e_1_2_1_15_1"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/019459988709700501","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/019459988709700501","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T14:27:24Z","timestamp":1760970444000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1177\/019459988709700501"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,11]]},"references-count":14,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1987,11]]}},"alternative-id":["10.1177\/019459988709700501"],"URL":"https:\/\/doi.org\/10.1177\/019459988709700501","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"type":"print","value":"0194-5998"},{"type":"electronic","value":"1097-6817"}],"subject":[],"published":{"date-parts":[[1987,11]]}}}