{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T23:04:10Z","timestamp":1767827050210,"version":"3.49.0"},"reference-count":17,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,4,22]],"date-time":"2016-04-22T00:00:00Z","timestamp":1461283200000},"content-version":"vor","delay-in-days":9883,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[1989,4]]},"abstract":"<jats:p>Lymphoepithelioma is common in the nasopharynx, but its presence elsewhere in Waldeyer's ring is rare. Thirteen patients with lymphoepithelioma in the tonsil and base of the tongue have been treated at our institution. At Initial examination, all 13 patients had advanced clinical disease. Five years after their initial treatment, seven patients were alive and free of disease. Radiation therapy controlled local and regional disease in 10 (77%) patients, yet three of these died of distant metastasis. Patients with lymphoepithelioma have a significantly better prognosis (<jats:italic>p<\/jats:italic> &lt; 0.05) than do patients with either nonkerafinizing or keratinizing high\u2010grade oropharyngeal carcinoma. Early recognition and combined therapy may further improve the prognosis. Differentiation of lymphoepithelioma from other high\u2010grade squamous cell carcinomas of the oropharynx is important to guide treatment and to provide prognostic information.<\/jats:p>","DOI":"10.1177\/019459988910000410","type":"journal-article","created":{"date-parts":[[2015,8,18]],"date-time":"2015-08-18T03:09:03Z","timestamp":1439867343000},"page":"303-307","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Lymphoepithelioma of the Oropharynx"],"prefix":"10.1002","volume":"100","author":[{"given":"Stephen F.","family":"Bansberg","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology Rochester Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kerry D.","family":"Olsen","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Rochester Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas A.","family":"Gaffey","sequence":"additional","affiliation":[{"name":"Section of Surgical Pathology Mayo Clinic and Mayo Foundation Rochester Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,4,22]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bdj.4803502"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(41)90508-1"},{"key":"e_1_2_1_4_1","first-page":"243","volume-title":"Tumors of the oral cavity and pharynx. 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