{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T18:37:19Z","timestamp":1760985439754,"version":"build-2065373602"},"reference-count":16,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,4,22]],"date-time":"2016-04-22T00:00:00Z","timestamp":1461283200000},"content-version":"vor","delay-in-days":9335,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[1990,10]]},"abstract":"<jats:p>The etiology of an asymmetric sensorineural hearing loss can often be difficult to determine. Because a wide variety of pathologic processes may be responsible for the hearing loss, numerous diagnostic tests are usually used in the initial evaluation, including pure\u2010tone audiometry, acoustic reflex testing, imaging, serologic testing, and auditory brainstem response testing. The diagnostic evaluations of 225 consecutive cases of asymmetric sensorineural hearing loss are reviewed. A cochlear slte\u2010of\u2010lesion was demonstrated in the majority (194) of patients. Because all retrocochlear lesions (31) were associated with an abnormal auditory brainstem response, imaging should be performed in that group of patients. Magnetic resonance imaging offers greater specificity than computed tomography. Reflex decay, acoustic reflex testing, and rollover were all associated with a high false\u2010negative rate. Whereas serologic testing for syphilis yielded several cases of otosyphilis, thyroid function testing was of little value. A diagnostic protocol for asymmetric sensorineural hearing loss is presented.<\/jats:p>","DOI":"10.1177\/019459989010300411","type":"journal-article","created":{"date-parts":[[2016,4,21]],"date-time":"2016-04-21T12:40:47Z","timestamp":1461242447000},"page":"593-598","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["The use of diagnostic testing in asymmetric sensorineural hearing loss"],"prefix":"10.1002","volume":"103","author":[{"given":"Robert A.","family":"Hendrix","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology and Human Communication Hospital of the University of Pennsylvania Philadelphia Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert M.","family":"Dedio","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology and Human Communication Hospital of the University of Pennsylvania Philadelphia Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony P.","family":"Sclafani","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology and Human Communication Hospital of the University of Pennsylvania Philadelphia Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,4,22]]},"reference":[{"volume-title":"Interpretation of diagnostic tests for acoustic neuroma","year":"1984","author":"Gates G","key":"e_1_2_1_2_1"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016487809124741"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1980.00790280026005"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-197812000-00001"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(20)31865-X"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-197907000-00001"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1979.00790180003001"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198601000-00003"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1985.00800030051004"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410200518"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198704000-00012"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.162.2.3492010"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348948609500104"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1988.03410220097036"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016488009124955"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.1987.tb00173.x"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/019459989010300411","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/019459989010300411","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T14:28:12Z","timestamp":1760970492000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1177\/019459989010300411"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,10]]},"references-count":16,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1990,10]]}},"alternative-id":["10.1177\/019459989010300411"],"URL":"https:\/\/doi.org\/10.1177\/019459989010300411","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"type":"print","value":"0194-5998"},{"type":"electronic","value":"1097-6817"}],"subject":[],"published":{"date-parts":[[1990,10]]},"assertion":[{"value":"1989-06-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1990-04-03","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-04-22","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}