{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T23:33:59Z","timestamp":1792020839705,"version":"4.4.0"},"reference-count":14,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[1991,6,1]],"date-time":"1991-06-01T00:00:00Z","timestamp":675734400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[1991,6]]},"abstract":"<jats:p>The etiology, pathophysiology, and natural history of Meniere's syndrome are poorly understood. The reported studies have had inadequate followup or insufficient numbers of patients to allow conclusions about the natural history. Our study group was 119 patients who had the classic symptom complex of episodic vertigo, tinnitus, and hearing loss in the year 1970. After initial review of these charts, follow\u2010up information was obtained by questionnaire, telephone interview, chart review, or repeat examination, when possible, both in 1983 and in 1988, for a total followup of 18 years. In the patients with followups of at least 14 years, vertiginous episodes had disappeared completely in 50% of patients and somewhat resolved in 28%; hearing was absent in 48% and worse in 21%. Surprisingly, 43% of patients underwent surgery at some point for control of vertigo. Bilateral disease was present initially in 13% and developed subsequently in 45% of patients. Other areas reviewed included the efficacy of long\u2010term medical treatment, frequency and severity of vertiginous attacks, and contralateral ear symptoms.<\/jats:p>","DOI":"10.1177\/019459989110400603","type":"journal-article","created":{"date-parts":[[2015,11,25]],"date-time":"2015-11-25T06:44:15Z","timestamp":1448433855000},"page":"783-788","source":"Crossref","is-referenced-by-count":88,"title":["Longitudinal followup of patients with meniere's disease"],"prefix":"10.1002","volume":"104","author":[{"suffix":"JR.","given":"J. Douglas","family":"Green","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology Mayo Clinic and Mayo Foundation Rochester Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel J.","family":"Blum","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Mayo Clinic and Mayo Foundation Rochester Minnesota"},{"name":"Wolfe Clinic, Marshalltown, Iowa Rochester Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen G.","family":"Harner","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Mayo Clinic and Mayo Foundation Rochester Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[1991,6]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1288\/00005537-197209000-00011","article-title":"Meniere's disease: results of the two\u2010and\u2010one\u2010half\u2010year study of etiology, natural history, and results of treatment","volume":"82","author":"M\u00e9ni\u00e8re P","year":"1972","journal-title":"Laryngoscope"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1942.00670010861002"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100003947"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/00034894800896S201"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/019459988910000102"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1981.00790410009002"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1975.00780390022006"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(20)33313-2"},{"key":"e_1_2_1_10_1","first-page":"2429","article-title":"Vestibulogene vertigo","volume":"103","author":"Jongkees LBW","year":"1959","journal-title":"Ned Tijdschr Geneeskd"},{"key":"e_1_2_1_11_1","first-page":"72","article-title":"The natural course of M\u00e9ni\u00e8re's disease","volume":"406","author":"Friberg U","year":"1984","journal-title":"Acta Otolaryngol Suppl (Stockh)"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/003591577106400823"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(20)32940-6"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348946507400407"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016487609107484"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/019459989110400603","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/019459989110400603","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T11:58:49Z","timestamp":1760961529000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1177\/019459989110400603"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,6]]},"references-count":14,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1991,6]]}},"alternative-id":["10.1177\/019459989110400603"],"URL":"https:\/\/doi.org\/10.1177\/019459989110400603","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"value":"0194-5998","type":"print"},{"value":"1097-6817","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,6]]}}}