{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T10:47:40Z","timestamp":1761648460877,"version":"build-2065373602"},"reference-count":17,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,5,18]],"date-time":"2016-05-18T00:00:00Z","timestamp":1463529600000},"content-version":"vor","delay-in-days":9088,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[1991,7]]},"abstract":"<jats:p>The otolaryngologist\u2010head and neck surgeon is frequently consulted to evaluate patients before the administration of myelosuppressive cancer chemotherapy. Fifty consecutive patients treated at the University of Pennsylvania Oncology Center were studied before and during chemotherapy for adult leukemia or bone marrow transplantation. Otolaryngic history, physical examination, radiographic studies, and hematologic surveys were analyzed for the duration of therapy in an attempt to identify risk factors for infectious and hematologic otolaryngic complications. Two\u2010thirds of the patients studied experienced untoward effects that required the further attention of an otolaryngologist\u2010head and neck surgeon. The various complications and associated correlations with the study parameters before and during chemotherapy are discussed.<\/jats:p>","DOI":"10.1177\/019459989110500114","type":"journal-article","created":{"date-parts":[[2017,7,3]],"date-time":"2017-07-03T03:44:16Z","timestamp":1499053456000},"page":"101-106","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The infectious and hematologic otolaryngic complications of myelosuppressive cancer chemotherapy"],"prefix":"10.1002","volume":"105","author":[{"given":"Laurence J.","family":"Dinardo","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology and Human Communications Hospital of the University of Pennsylvania Philadelphia Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert A.","family":"Hendrix","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology and Human Communications Hospital of the University of Pennsylvania Philadelphia Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,5,18]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-7125(16)32514-7"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1967.03130120031008"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-77-5-707"},{"key":"e_1_2_1_5_1","first-page":"141","article-title":"Management of infections in patients with leukemia and lymphoma: Current concepts and experimental approaches","volume":"9","author":"Levine AS","year":"1972","journal-title":"Semin Hematol"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1988.00380120031007"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197703)39:3<1345::AID-CNCR2820390350>3.0.CO;2-R"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(78)90188-2"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.1966.tb04691.x"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/00325481.1982.11716097"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.2890080612"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19881101)62:9<2042::AID-CNCR2820620928>3.0.CO;2-D"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/019459989010200404"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(87)90196-4"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19860715)58:2<366::AID-CNCR2820580228>3.0.CO;2-V"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.2890080205"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(83)80774-4"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.3109\/10408368009106445"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/019459989110500114","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/019459989110500114","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T12:29:39Z","timestamp":1760963379000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1177\/019459989110500114"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,7]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1991,7]]}},"alternative-id":["10.1177\/019459989110500114"],"URL":"https:\/\/doi.org\/10.1177\/019459989110500114","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"type":"print","value":"0194-5998"},{"type":"electronic","value":"1097-6817"}],"subject":[],"published":{"date-parts":[[1991,7]]},"assertion":[{"value":"1990-09-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1991-02-27","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-05-18","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}