{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T00:24:36Z","timestamp":1792196676374,"version":"4.4.0"},"reference-count":16,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,7,19]],"date-time":"2016-07-19T00:00:00Z","timestamp":1468886400000},"content-version":"vor","delay-in-days":8875,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[1992,4]]},"abstract":"<jats:p>Although adenoid cystic carcinoma may be found in multiple sites in the head and neck as well as other glandular sites throughout the body, nowhere is management of the disease more controversial than in the parotid gland. Here the facial nerve is at risk from both the disease and the treatment. Seventy\u2010five cases of adenoid cystic carcinoma of the parotid were analyzed. Patients were placed in four groups, depending on the type of parotid surgery received as definitive therapy: (1) lateral lobectomy, (2) total parotidectomy, (3) radical parotidectomy without preoperative facial weakness, and (4) radical parotidectomy with preoperative facial weakness. Patients were assessed with regard to staging of the initial lesion, the status of surgical margins, and the use of postoperative radiotherapy. The incidence of local recurrence and distant metastases were also recorded. Survival statistics are presented for each group. Though associated with facial nerve sacrifice, radical parotidectomy appears to offer clear advantages in terms of long\u2010term disease\u2010free survival in patients with T<jats:sub>2<\/jats:sub> and T<jats:sub>3<\/jats:sub> lesions. The residual facial paralysis may be rehabilitated primarily or secondarily to reduce patient morbidity. Four of 16 patients (25%) with preoperative weakness achieved 10\u2010year survival when radical parotidectomy was used. Obtaining clear margins at the initial setting appears to offer improved survival.<\/jats:p>","DOI":"10.1177\/019459989210600403","type":"journal-article","created":{"date-parts":[[2017,1,28]],"date-time":"2017-01-28T03:58:05Z","timestamp":1485575885000},"page":"332-338","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["Surgical Management of Adenoid Cystic Carcinoma in the Parotid Gland"],"prefix":"10.1002","volume":"106","author":[{"given":"John D.","family":"Casler","sequence":"first","affiliation":[{"name":"Otolaryngology Service\u2010Head and Neck Surgery Walter Reed Army Medical Center Washington, D.C."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John J.","family":"Conley","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery College of Physicians and Surgeons Columbia University New York New York"},{"name":"Department of Head and Neck Surgery St. Vincent's Medical Center New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,7,19]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1974.00780040087001"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(79)90423-9"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198410000-00011"},{"key":"e_1_2_1_5_1","first-page":"535","article-title":"The fate of recurrent or persistent parotid tumors","volume":"96","author":"Slaughter D","year":"1952","journal-title":"Surg Gynecol Obstet"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-196402000-00015"},{"key":"e_1_2_1_7_1","first-page":"389","article-title":"An analysis of fifty carcinomas of the salivary glands","volume":"8","author":"Luccioli G","year":"1965","journal-title":"Can J Surg"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(72)90069-4"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1972.00770080494002"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(74)90265-7"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348947708600302"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198502000-00009"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/019459988509300309"},{"key":"e_1_2_1_14_1","first-page":"828","article-title":"Conservation surgery in the management of adenoid cystic carcinoma of the head and neck","volume":"62","author":"Harrison D","year":"1986","journal-title":"Bull NY Acad Med"},{"key":"e_1_2_1_15_1","first-page":"167","article-title":"In discussion: May M, Hughes GB. 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