{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T12:52:24Z","timestamp":1793364744911,"version":"4.5.0"},"reference-count":10,"publisher":"Wiley","issue":"6P2","license":[{"start":{"date-parts":[[2016,12,13]],"date-time":"2016-12-13T00:00:00Z","timestamp":1481587200000},"content-version":"vor","delay-in-days":8778,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[1992,12]]},"abstract":"<jats:p>Vasomotor rhinitis is a nonspecific disorder that is caused neither by infection nor allergy but rather by an imbalance of the autonomic nervous system with a preponderant action of parasympathetic fibers on nasal blood vessels. Rhinitis during pregnancy appears to result from the increased production of estrogen; increased estrogen levels caused by treatment, puberty, or liver disease may also cause rhinitis. Nasal saline mist, antihistamines, and topical corticosteroids are recommended; intranasal corticosteroid injections are also useful but must be administered under expert care. Rhinitis medicamentosa results from overuse of topical vasoconstrictors, which produce a rebound phenomenon. Rebound can also result from numerous medications, including antihypertensive preparations that reduce catecholamine levels, antidepressants, antipsychotics, and tranquilizers. Management of rhinitis medicamentosa consists in limiting the use of vasoconstrictors to no more than 3 days and giving the patient saline nasal sprays, daytime oral vasoconstrictors, and nocturnal antihistamines. Corticosteroids, preferably topical nasal steroids rather than even a short\u2010term course of systemic administration, should also be used.<\/jats:p>","DOI":"10.1177\/019459989210700606.2","type":"journal-article","created":{"date-parts":[[2017,1,5]],"date-time":"2017-01-05T16:25:10Z","timestamp":1483633510000},"page":"845-849","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Rhinitis during pregnancy and rhinitis medicamentosa"],"prefix":"10.1002","volume":"107","author":[{"given":"Mary D.","family":"Lekas","sequence":"first","affiliation":[{"name":"Providence Rhode Island"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,12,13]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"573","volume-title":"Smell and taste in health and disease.","author":"Lekas M","year":"1991"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-198608000-00012"},{"key":"e_1_2_1_4_1","first-page":"313","article-title":"Changes in form and function of mucous membranes occurring as part of protective reaction patterns in man during periods of life stress and emotional conflict","volume":"61","author":"Wolff HG","year":"1948","journal-title":"Trans Assoc Am Physicians"},{"key":"e_1_2_1_5_1","first-page":"248","volume-title":"Surgical diseases in pregnancy.","author":"Lewis JH","year":"1974"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-198207000-00013"},{"key":"e_1_2_1_7_1","first-page":"16","article-title":"The management of nasal obstruction during pregnancy","volume":"62","author":"Mabry RL","year":"1983","journal-title":"Ear Nose Throat J"},{"key":"e_1_2_1_8_1","first-page":"29","article-title":"Prescribing practiced during pregnancy","volume":"21","author":"Goplerud CP","year":"1981","journal-title":"Consultant"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/019459988108900224"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198110000-00005"},{"key":"e_1_2_1_11_1","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1288\/00005537-198707000-00010","article-title":"Neonatal respiratory distress from rhinitis medicamentosa","volume":"87","author":"Osguthorpe JD","year":"1987","journal-title":"Laryngoscope"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/019459989210700606.2","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/019459989210700606.2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:28:31Z","timestamp":1760956111000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1177\/019459989210700606.2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,12]]},"references-count":10,"journal-issue":{"issue":"6P2","published-print":{"date-parts":[[1992,12]]}},"alternative-id":["10.1177\/019459989210700606.2"],"URL":"https:\/\/doi.org\/10.1177\/019459989210700606.2","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"value":"0194-5998","type":"print"},{"value":"1097-6817","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,12]]},"assertion":[{"value":"2016-12-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}