{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:41:31Z","timestamp":1761007291743,"version":"build-2065373602"},"reference-count":17,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[1993,6,1]],"date-time":"1993-06-01T00:00:00Z","timestamp":738892800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[1993,6]]},"abstract":"<jats:p>DNA analysis by flow cytometry is considered to be of prognostic value in epidermoid carcinoma of the head and neck. However, few and contradictory studies have been made on laryngeal carcinomas. We studied 48 epidermoid carcinomas in patients subjected to horizontal supraglottic laryngectomy with a 5\u2010year\u2010 followup. The technique described by Hedley for fixated and paraffin\u2010embedded tumors was used. Thirteen tumors were excluded on the grounds of presenting variation coefficients in excess of 10. Of the 35 cases analyzed, 28 (80%) were diploid and seven (20%) aneuploid. No correlation was observed between tumor ploldy and patient survival, recurrence, or any of the histopathological variables studied.<\/jats:p>","DOI":"10.1177\/019459989310800613","type":"journal-article","created":{"date-parts":[[2015,11,25]],"date-time":"2015-11-25T06:49:46Z","timestamp":1448434186000},"page":"706-710","source":"Crossref","is-referenced-by-count":13,"title":["Analysis of DNA Content in Supraglottic Epidermoid Carcinoma"],"prefix":"10.1002","volume":"108","author":[{"given":"Rafael Barona","family":"de Guzman","sequence":"first","affiliation":[{"name":"Department of Otolaryngology General Hospital Valencia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. 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