{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T16:43:13Z","timestamp":1762101793333,"version":"build-2065373602"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[1994,7,1]],"date-time":"1994-07-01T00:00:00Z","timestamp":773020800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[1994,7]]},"abstract":"<jats:p>It is well known that the protective laryngeal closure is elicited by mechanical or chemical stimulation of the epithelium in the glottis. In this study we used light microscopic observation and relative examination of the intraepithelial nerve fibers in the glottis to clarify the perceptive mechanism using immunohistochemical methods. In the anterior glottis, a moderate number of protein gene product 9.5\u2010immunoreactive intraepithelial nerve fibers were observed, most of which were found to be located just anterior to the vocal process. The number of fibers in the upper surface of the vocal fold was larger than that in the free edge and the lower surface. Only a few calcitonin gene\u2010related polypeptide\u2010immunoreactive fibers were seen, and substance P\u2010immunoreactive fibers were rarely seen. On the other hand, a dense distribution of protein gene product 9.5\u2010immunoreactive nerve fibers was observed throughout the epithelium of the posterior glottis. The number of calcitonin gene\u2010related peptide\u2010immunoreactive fibers was about 20% that of protein gene product 9.5\u2010immunoreactive fibers, whereas the number of substance P\u2010immunoreactive fibers was only 1% to 2%. The results of this study suggest the possible existence of regional differences in the perceptive mechanism between the anterior and posterior glottis.<\/jats:p>","DOI":"10.1177\/019459989411100117","type":"journal-article","created":{"date-parts":[[2015,11,25]],"date-time":"2015-11-25T06:53:21Z","timestamp":1448434401000},"page":"91-99","source":"Crossref","is-referenced-by-count":10,"title":["Distribution of Intraepithelial Nerve Fibers in the Feline Glottis"],"prefix":"10.1002","volume":"111","author":[{"given":"Hiromichi","family":"Matsuo","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Saga Medical School Saga Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takemoto","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Saga Medical School Saga Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1994,7]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"501","volume-title":"Sudden infant death syndrome","author":"Sessle BJ","year":"1983"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1961.00740020005001"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1620\/tjem.58.199"},{"key":"e_1_2_1_5_1","first-page":"11","article-title":"Innervation especially the sensory innervation of the laryngeal mucous membrane except the epiglottis","volume":"45","author":"Matsumoto K","year":"1950","journal-title":"Tohoku Igaku Zassi"},{"key":"e_1_2_1_6_1","first-page":"330","article-title":"Morphological investigation of sensory nerve endings of the human larynx","volume":"31","author":"Watanabe S","year":"1985","journal-title":"Otol Fukuoka"},{"key":"e_1_2_1_7_1","first-page":"49","volume-title":"Vocal fold physiology Vol 2. 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