{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T15:16:50Z","timestamp":1777475810451,"version":"3.51.4"},"reference-count":16,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2004,3,1]],"date-time":"2004-03-01T00:00:00Z","timestamp":1078099200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Asian Cardiovasc Thorac Ann"],"published-print":{"date-parts":[[2004,3]]},"abstract":"<jats:p>Low-molecular-weight heparin and acetyl salicylic acid have become an established treatment for unstable angina. A retrospective study on our database of one year was carried out to see what impact preoperative low-molecular-weight heparin versus none had on the postoperative course of 473 patients having coronary surgery exclusively. Apart from the fact that the low-molecular-weight heparin patients had a higher New York Heart Association classification and marginally more grafts, longer bypass and cross-clamp time, the preoperative characteristics and surgery of the two groups were similar. The low-molecular-weight heparin group had twice as many (9.7% versus 4.7%) re-operations for bleeding, 46% versus 26% had blood transfusion and 22.3% versus 12.6% plasma transfusion. The postoperative outcome was otherwise similar. Preoperative treatment of unstable angina with low-molecular-weight heparin carries a definite risk of postoperative bleeding. Although this study did not reveal any serious consequences, bleeding, transfusions and re-operations are associated with infections, wound healing problems and death. The indications and length of treatment with low-molecular-weight heparin in unstable angina patients have to be appropriate and the perioperative management of these patients has to address the bleeding tendency.<\/jats:p>","DOI":"10.1177\/021849230401200102","type":"journal-article","created":{"date-parts":[[2013,5,6]],"date-time":"2013-05-06T09:37:22Z","timestamp":1367833042000},"page":"3-6","source":"Crossref","is-referenced-by-count":5,"title":["Bleeding following Coronary Surgery after Preoperative Low-Molecular-Weight Heparin"],"prefix":"10.1177","volume":"12","author":[{"given":"Ulf","family":"Myhre","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roar","family":"Stenseth","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, St Elisabeth Heart Centre, Trondheim University Hospital, Trondheim, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asbj\u00f8rn","family":"Karevold","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lise","family":"Bjella","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, St Elisabeth Heart Centre, Trondheim University Hospital, Trondheim, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Per Snorre","family":"Lingaas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Per Olav","family":"Olsen","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, St Elisabeth Heart Centre, Trondheim University Hospital, Trondheim, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rune","family":"Haaverstad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Idar","family":"Kirkeby-Garstad","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, St Elisabeth Heart Centre, Trondheim University Hospital, Trondheim, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olaf Walle","family":"Levang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2004,3,1]]},"reference":[{"key":"bibr1-021849230401200102","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(96)91270-2"},{"key":"bibr2-021849230401200102","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(97)00485-2"},{"key":"bibr3-021849230401200102","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-199612000-00008"},{"key":"bibr4-021849230401200102","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(99)01366-1"},{"key":"bibr5-021849230401200102","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(96)70380-X"},{"key":"bibr6-021849230401200102","doi-asserted-by":"publisher","DOI":"10.1378\/chest.110.5.1173"},{"key":"bibr7-021849230401200102","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.133.4.442"},{"key":"bibr8-021849230401200102","doi-asserted-by":"publisher","DOI":"10.1378\/chest.119.5.1461"},{"key":"bibr9-021849230401200102","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8703(99)70461-8"},{"key":"bibr10-021849230401200102","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.96.12.4204"},{"key":"bibr11-021849230401200102","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.93.9.1651"},{"key":"bibr12-021849230401200102","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(96)00447-0"},{"key":"bibr13-021849230401200102","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(97)00489-X"},{"key":"bibr14-021849230401200102","first-page":"N51","volume":"19","author":"Lindahl B","year":"1998","journal-title":"Eur Heart J"},{"key":"bibr15-021849230401200102","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.10016"},{"key":"bibr16-021849230401200102","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(02)01954-X"}],"container-title":["Asian Cardiovascular and Thoracic Annals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/021849230401200102","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/021849230401200102","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/021849230401200102","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T13:54:15Z","timestamp":1777384455000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/021849230401200102"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,3]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2004,3]]}},"alternative-id":["10.1177\/021849230401200102"],"URL":"https:\/\/doi.org\/10.1177\/021849230401200102","relation":{},"ISSN":["0218-4923","1816-5370"],"issn-type":[{"value":"0218-4923","type":"print"},{"value":"1816-5370","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,3]]}}}