{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:05:06Z","timestamp":1787069106302,"version":"build-2736575974"},"reference-count":19,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2004,12,1]],"date-time":"2004-12-01T00:00:00Z","timestamp":1101859200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Asian Cardiovasc Thorac Ann"],"published-print":{"date-parts":[[2004,12]]},"abstract":"<jats:p>Infants with atrial septal defects are seldom symptomatic and usually require elective surgery between 2 and 4 years of age. However a small minority is symptomatic and management at this age has been controversial. This study evaluated surgical closure of atrial septal defect below 2 years of age. Eighteen infants with a mean age of 13.4 \u00b1 5.7 months were operated on for secundum atrial septal defect from 1994 to 2001. Fourteen patients were symptomatic with failure to thrive in 7 and recurrent respiratory infections in 7, one had increasing cardiomegaly, and 3 were operated on early for social reasons. The defect was isolated in 11 patients (61%) and the other 7 (39%) had minor associated lesions requiring additional procedures such as ductal ligation, direct closure of a tiny ventricular septal defect, and inspection of the mitral valve. There were no early or late deaths. The postoperative course was complicated by pulmonary problems in 4 cases. Of the 16 patients available for follow-up, 14 were asymptomatic and 2 were symptomatically improved. Most showed a dramatic improvement in growth and development. These gratifying results indicate that consideration should be given to early surgical closure of atrial septal defect in symptomatic infants.<\/jats:p>","DOI":"10.1177\/021849230401200404","type":"journal-article","created":{"date-parts":[[2013,5,6]],"date-time":"2013-05-06T09:37:22Z","timestamp":1367833042000},"page":"296-299","source":"Crossref","is-referenced-by-count":7,"title":["Surgical Closure of Atrial Septal Defect in Children under Two Years of Age"],"prefix":"10.1177","volume":"12","author":[{"given":"Usha","family":"Parvathy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Komarakshi R","family":"Balakrishnan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madathil S","family":"Ranjith","sequence":"additional","affiliation":[{"name":"Department of Cardiology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Saldanha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahesh","family":"Vakamudi","sequence":"additional","affiliation":[{"name":"Department of Cardiac Anaesthesia, Sri Ramachandra Medical College University Hospital, Chennai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2004,12,1]]},"reference":[{"key":"bibr1-021849230401200404","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(65)90331-0"},{"key":"bibr2-021849230401200404","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(73)90164-6"},{"key":"bibr3-021849230401200404","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.47.5.1042"},{"key":"bibr4-021849230401200404","first-page":"94","volume":"29","author":"Gordovilla ZG","year":"1988","journal-title":"An Esp Pediatr"},{"key":"bibr5-021849230401200404","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(88)90259-1"},{"key":"bibr6-021849230401200404","first-page":"1115","volume":"140","author":"Mahoney LT","year":"1986","journal-title":"Am J Dis Child"},{"key":"bibr7-021849230401200404","first-page":"1079","volume":"30","author":"Joshi NC","year":"1993","journal-title":"Indian Pediatr"},{"key":"bibr8-021849230401200404","first-page":"399","volume":"30","author":"Wyler F","year":"1976","journal-title":"Helv Paediatr Acta"},{"key":"bibr9-021849230401200404","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(67)90549-8"},{"key":"bibr10-021849230401200404","doi-asserted-by":"publisher","DOI":"10.1378\/chest.75.3.395"},{"key":"bibr11-021849230401200404","first-page":"905","volume":"10","author":"Suarez CP","year":"1977","journal-title":"An Esp Pediatr"},{"key":"bibr12-021849230401200404","doi-asserted-by":"publisher","DOI":"10.1136\/adc.56.10.784"},{"key":"bibr13-021849230401200404","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8191.1996.tb00024.x"},{"key":"bibr14-021849230401200404","doi-asserted-by":"publisher","DOI":"10.1007\/PL00021008"},{"key":"bibr15-021849230401200404","doi-asserted-by":"publisher","DOI":"10.1007\/BF03007617"},{"key":"bibr16-021849230401200404","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(19)40207-9"},{"key":"bibr17-021849230401200404","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(62)90031-5"},{"key":"bibr18-021849230401200404","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(19)40300-0"},{"key":"bibr19-021849230401200404","first-page":"25","volume":"14","author":"Navajas A","year":"1981","journal-title":"An Esp Pediatr"}],"container-title":["Asian Cardiovascular and Thoracic Annals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/021849230401200404","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/021849230401200404","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/021849230401200404","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T13:54:33Z","timestamp":1777384473000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/021849230401200404"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,12]]},"references-count":19,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2004,12]]}},"alternative-id":["10.1177\/021849230401200404"],"URL":"https:\/\/doi.org\/10.1177\/021849230401200404","relation":{},"ISSN":["0218-4923","1816-5370"],"issn-type":[{"value":"0218-4923","type":"print"},{"value":"1816-5370","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,12]]}}}