{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T22:00:58Z","timestamp":1777500058740,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2008,8,1]],"date-time":"2008-08-01T00:00:00Z","timestamp":1217548800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Asian Cardiovasc Thorac Ann"],"published-print":{"date-parts":[[2008,8]]},"abstract":"<jats:p>Cardiac troponin levels are frequently elevated in patients with chronic renal failure, hence diagnosis of myocardial necrosis is difficult. The prevalence of elevated serum troponin T was determined and its diagnostic value in acute coronary syndrome was assessed in patients with chronic renal insufficiency. A retrospective cross-sectional analysis was performed in 227 patients with chronic renal insufficiency and a diagnosis of unstable angina, non-ST or ST-segment elevation myocardial infarction. All patients had baseline serum troponin T levels measured at previous visits; the baseline troponin T level was raised in 53.3%. Cardiac troponin T levels did not correlate with creatinine levels, and were not affected by dialysis. Mortality after an acute coronary event was high (46.3%). Because of the elevated baseline cardiac troponin T levels, detection of acute coronary syndrome in patients with chronic renal failure requires evaluation of serial cardiac enzyme measurements and serial 12-lead electrocardiograms. Early and definitive cardiac interventions may contribute towards decreasing the mortality rate in this group of patients.<\/jats:p>","DOI":"10.1177\/021849230801600405","type":"journal-article","created":{"date-parts":[[2013,5,6]],"date-time":"2013-05-06T09:37:22Z","timestamp":1367833042000},"page":"284-287","source":"Crossref","is-referenced-by-count":3,"title":["Cardiac Troponin T in Acute Coronary Syndrome with Renal Insufficiency"],"prefix":"10.1177","volume":"16","author":[{"given":"Huck Chin","family":"Chew","sequence":"first","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2008,8,1]]},"reference":[{"key":"bibr1-021849230801600405","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199712043372302"},{"key":"bibr2-021849230801600405","first-page":"853","volume":"35","author":"Hutter AM","year":"2000","journal-title":"J Am Coll Cardiol"},{"key":"bibr3-021849230801600405","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(99)00870-X"},{"key":"bibr4-021849230801600405","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199610313351802"},{"key":"bibr5-021849230801600405","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/45.2.199"},{"key":"bibr6-021849230801600405","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.94.6.1291"},{"key":"bibr7-021849230801600405","doi-asserted-by":"publisher","DOI":"10.1067\/mhj.2000.106915"},{"key":"bibr8-021849230801600405","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.93.9.1651"},{"key":"bibr9-021849230801600405","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(01)01388-2"},{"key":"bibr10-021849230801600405","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.98.18.1853"},{"key":"bibr11-021849230801600405","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.103.14.1832"},{"key":"bibr12-021849230801600405","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199610313351801"},{"key":"bibr13-021849230801600405","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(02)02608-6"},{"key":"bibr14-021849230801600405","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/44.7.1410"},{"key":"bibr15-021849230801600405","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/16.7.1452"},{"key":"bibr16-021849230801600405","first-page":"907","volume":"19","author":"Choy JB","year":"2003","journal-title":"Can J Cardiol"},{"key":"bibr17-021849230801600405","first-page":"1541","volume":"165","author":"Jensen JK","year":"2003","journal-title":"Ugeskr Laeger"},{"key":"bibr18-021849230801600405","doi-asserted-by":"publisher","DOI":"10.1007\/s00063-003-1243-3"},{"key":"bibr19-021849230801600405","doi-asserted-by":"publisher","DOI":"10.1016\/S0009-9120(99)00064-8"},{"key":"bibr20-021849230801600405","doi-asserted-by":"publisher","DOI":"10.1515\/CCLM.2002.039"}],"container-title":["Asian Cardiovascular and Thoracic Annals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/021849230801600405","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/021849230801600405","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/021849230801600405","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:13:46Z","timestamp":1777389226000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/021849230801600405"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,8]]},"references-count":20,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008,8]]}},"alternative-id":["10.1177\/021849230801600405"],"URL":"https:\/\/doi.org\/10.1177\/021849230801600405","relation":{},"ISSN":["0218-4923","1816-5370"],"issn-type":[{"value":"0218-4923","type":"print"},{"value":"1816-5370","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,8]]}}}