{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T05:20:43Z","timestamp":1777526443542,"version":"3.51.4"},"reference-count":18,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2015,4,2]],"date-time":"2015-04-02T00:00:00Z","timestamp":1427932800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Asian Cardiovasc Thorac Ann"],"published-print":{"date-parts":[[2015,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Pulmonary vein isolation has been employed to eliminate paroxysmal atrial fibrillation. However, the long-term outcome in terms of long-standing persistent atrial fibrillation is unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>One hundred patients with rheumatic mitral valve disease and long-standing (&gt;1 year) persistent atrial fibrillation were operated on between July 1998 and June 2007. Mitral valve surgery and surgical isolation (cut-and-sew) of the pulmonary veins were performed in all cases. Transthoracic echocardiography and 24-h Holter monitoring were obtained after 3 and 6 months and yearly thereafter.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Early and late follow-up was 99% and 92% complete, respectively. The endpoint was freedom from atrial fibrillation. There was one (1%) hospital death. Atrial fibrillation was present in 39%, 47%, 63% and 68% of patients at 3 months, 1 year, 3 years, and 5 years after surgery, respectively. The odds ratios for recurrence of atrial fibrillation postoperatively were 1.41 (95% confidence interval 1.14\u20131.74), 2.17 (95% confidence interval 1.63\u20132.90), and 3.62 (95% confidence interval 2.44\u20135.38) at 1 week, 3 years, and 5 years, respectively. Actuarial freedom from atrial fibrillation was 35% at 3 years, and 30% at 5 years. A direct relationship was observed between preoperative left atrial size &gt;6\u2009cm and atrial fibrillation recurrence at 5 years ( p\u2009&lt;\u20090.05 odds ratio\u2009=\u20092.5, 95% confidence interval 1.15\u2009\u2013\u20095.4).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>No beneficial effects of simple pulmonary vein isolation for long-standing persistent atrial fibrillation concomitant with rheumatic mitral valve disease were observed. Atrial fibrillation cannot be fully treated using only pulmonary vein isolation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0218492315581265","type":"journal-article","created":{"date-parts":[[2015,4,3]],"date-time":"2015-04-03T12:37:30Z","timestamp":1428064650000},"page":"665-669","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Pulmonary vein isolation for persistent atrial fibrillation. Long-term results"],"prefix":"10.1177","volume":"23","author":[{"given":"Ovidio A","family":"Garcia-Villarreal","sequence":"first","affiliation":[{"name":"Department of Cardiac Surgery. Hospital of Cardiology UMAE 34, IMSS, Monterrey, Nuevo Leon, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2015,4,2]]},"reference":[{"key":"bibr1-0218492315581265","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199809033391003"},{"key":"bibr2-0218492315581265","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(00)02376-6"},{"key":"bibr3-0218492315581265","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eus027"},{"key":"bibr4-0218492315581265","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.95.3.572"},{"key":"bibr5-0218492315581265","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-13-0468"},{"key":"bibr6-0218492315581265","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.109.856633"},{"key":"bibr7-0218492315581265","doi-asserted-by":"publisher","DOI":"10.2174\/157340312803760802"},{"key":"bibr8-0218492315581265","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2007.11.021"},{"key":"bibr9-0218492315581265","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.111.968032"},{"key":"bibr10-0218492315581265","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2010.01.017"},{"key":"bibr11-0218492315581265","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.09.076"},{"key":"bibr12-0218492315581265","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.111.966523"},{"key":"bibr13-0218492315581265","doi-asserted-by":"publisher","DOI":"10.1046\/j.1540-8167.2003.03136.x"},{"key":"bibr14-0218492315581265","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(96)00613-3"},{"key":"bibr15-0218492315581265","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(01)03596-2"},{"key":"bibr16-0218492315581265","doi-asserted-by":"publisher","DOI":"10.5761\/atcs.oa.11.01733"},{"key":"bibr17-0218492315581265","first-page":"80","volume":"3","author":"Cox JL","year":"2014","journal-title":"Ann Cardiothorac Surg"},{"key":"bibr18-0218492315581265","doi-asserted-by":"publisher","DOI":"10.1016\/S0008-6363(02)00258-4"}],"container-title":["Asian Cardiovascular and Thoracic Annals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0218492315581265","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0218492315581265","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0218492315581265","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:29:53Z","timestamp":1777393793000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0218492315581265"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4,2]]},"references-count":18,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,7]]}},"alternative-id":["10.1177\/0218492315581265"],"URL":"https:\/\/doi.org\/10.1177\/0218492315581265","relation":{},"ISSN":["0218-4923","1816-5370"],"issn-type":[{"value":"0218-4923","type":"print"},{"value":"1816-5370","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4,2]]}}}