{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T12:15:00Z","timestamp":1777551300903,"version":"3.51.4"},"reference-count":8,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2017,3,23]],"date-time":"2017-03-23T00:00:00Z","timestamp":1490227200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Asian Cardiovasc Thorac Ann"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:p>In cardiac surgery, supplementation with recombinant factor VIIa is the treatment of choice for patients with factor VII deficiency, but overzealous administration can be associated with thromboembolic side-effects. A 53-year-old man with factor VII activity 15.2%, international normalized ratio 2.9, and acute thrombotic critical coronary anatomy, underwent coronary artery bypass surgery and a thoracotomy with decortication 5 months later. He was managed successfully without recombinant factor VIIa supplementation. This case demonstrates that current bedside and laboratory tests such as thromboelastography, prothrombin time or international normalized ratio, and factor VII activity may not predict replacement therapy in these patients.<\/jats:p>","DOI":"10.1177\/0218492317702784","type":"journal-article","created":{"date-parts":[[2017,3,24]],"date-time":"2017-03-24T02:38:53Z","timestamp":1490323133000},"page":"42-44","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Factor VII deficiency: do all need replacement for cardiac surgery?"],"prefix":"10.1177","volume":"27","author":[{"given":"Fayaz Mohammed","family":"Khazi","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery, Dubai Hospital, Dubai, United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nayyer R","family":"Siddiqi","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Dubai Hospital, Dubai, United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yehia M","family":"Karaly","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Dubai Hospital, Dubai, United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bassil","family":"Al-Zamkan","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Dubai Hospital, Dubai, United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Faouzi DIT","family":"Safadi","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Dubai Hospital, Dubai, United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Obaid","family":"Al-Jassim","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Dubai Hospital, Dubai, United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,3,23]]},"reference":[{"key":"bibr1-0218492317702784","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2004.00944.x"},{"key":"bibr2-0218492317702784","doi-asserted-by":"publisher","DOI":"10.1160\/TH05-06-0407"},{"key":"bibr3-0218492317702784","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2010.11.078"},{"key":"bibr4-0218492317702784","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.834275"},{"key":"bibr5-0218492317702784","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aei244"},{"key":"bibr6-0218492317702784","first-page":"704","volume":"89","author":"Giansily-Blaizot M","year":"2004","journal-title":"Haematologica"},{"key":"bibr7-0218492317702784","doi-asserted-by":"publisher","DOI":"10.1111\/hae.12164"},{"key":"bibr8-0218492317702784","doi-asserted-by":"publisher","DOI":"10.1160\/TH07-04-0264"}],"container-title":["Asian Cardiovascular and Thoracic Annals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0218492317702784","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0218492317702784","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0218492317702784","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T17:53:57Z","timestamp":1777398837000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0218492317702784"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3,23]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["10.1177\/0218492317702784"],"URL":"https:\/\/doi.org\/10.1177\/0218492317702784","relation":{},"ISSN":["0218-4923","1816-5370"],"issn-type":[{"value":"0218-4923","type":"print"},{"value":"1816-5370","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3,23]]}}}