{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T12:12:49Z","timestamp":1777551169669,"version":"3.51.4"},"reference-count":8,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2018,2,7]],"date-time":"2018-02-07T00:00:00Z","timestamp":1517961600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Asian Cardiovasc Thorac Ann"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:p>Thymic carcinoma with central nervous system involvement is very rare in children. A 27-month-old girl presented with a unilateral squint, vomiting, and behavioral changes. Imaging studies showed a silent anterior mediastinal mass and a large metastatic mass at the base of the skull. Biopsy of the anterior mediastinal mass confirmed an undifferentiated tumor consistent with thymic carcinoma. The child died within 3 months of the onset of symptoms, due to progression of the disease. These lethal tumors of unknown histogeneses and etiology are aggressive in nature, resistant to therapy, and have a rapidly fatal course.<\/jats:p>","DOI":"10.1177\/0218492318759346","type":"journal-article","created":{"date-parts":[[2018,2,7]],"date-time":"2018-02-07T07:31:37Z","timestamp":1517988697000},"page":"239-241","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Undifferentiated thymic carcinoma with intracranial metastasis in a two-year-old"],"prefix":"10.1177","volume":"26","author":[{"given":"Nuthan","family":"Kumar","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Christian Medical College and Hospital, Vellore, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Narendra","family":"Chaudhary","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Christian Medical College and Hospital, Vellore, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne Jennifer","family":"Prabhu","sequence":"additional","affiliation":[{"name":"Department of Pathology, Christian Medical College and Hospital, Vellore, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leena","family":"Robinson Vimala","sequence":"additional","affiliation":[{"name":"Department of Radiology, Christian Medical College and Hospital, Vellore, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deepthi","family":"Boddu","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Christian Medical College and Hospital, Vellore, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leni Grace","family":"Mathew","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Christian Medical College and Hospital, Vellore, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,2,7]]},"reference":[{"key":"bibr1-0218492318759346","doi-asserted-by":"publisher","DOI":"10.1007\/BF02303555"},{"key":"bibr2-0218492318759346","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(03)00555-1"},{"key":"bibr3-0218492318759346","first-page":"41","volume":"19","author":"Yang JT","year":"2010","journal-title":"Acta Neurol Taiwan"},{"key":"bibr4-0218492318759346","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.10226"},{"key":"bibr5-0218492318759346","doi-asserted-by":"publisher","DOI":"10.1097\/JTO.0b013e3181f20c05"},{"key":"bibr6-0218492318759346","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.20468"},{"key":"bibr7-0218492318759346","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.25159"},{"key":"bibr8-0218492318759346","doi-asserted-by":"publisher","DOI":"10.1097\/JTO.0000000000000654"}],"container-title":["Asian Cardiovascular and Thoracic Annals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0218492318759346","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0218492318759346","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0218492318759346","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T17:53:32Z","timestamp":1777398812000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0218492318759346"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2,7]]},"references-count":8,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,3]]}},"alternative-id":["10.1177\/0218492318759346"],"URL":"https:\/\/doi.org\/10.1177\/0218492318759346","relation":{},"ISSN":["0218-4923","1816-5370"],"issn-type":[{"value":"0218-4923","type":"print"},{"value":"1816-5370","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,2,7]]}}}