{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T12:15:46Z","timestamp":1777551346450,"version":"3.51.4"},"reference-count":22,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2019,1,19]],"date-time":"2019-01-19T00:00:00Z","timestamp":1547856000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Asian Cardiovasc Thorac Ann"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Small-cell lung cancer is a highly aggressive and metastatic epithelial lung malignancy. A small percentage of these tumors can be detected at an early stage and may be appropriate for surgical treatment. We analyzed the data of patients with early-stage small-cell lung cancer who underwent lobectomy and mediastinal lymph node dissection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Between January 2011 and December 2016, 26 patients with early-stage small-cell lung cancer underwent lobectomy and mediastinal lymph node dissection and were included the study. The mean age was 60.9 years and 18 (69.2%) were male. Patients with increased uptake of\n                      <jats:sup>18<\/jats:sup>\n                      F-fludeoxyglucose in mediastinal or distant organs on positron-emission tomography computed tomography, or lung resections other than lobectomy, were not included in the study.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The most common tumor location was the right upper lobe. The diagnoses were achieved by intraoperative frozen section study in almost all patients (92.3%). Mean overall survival was 58.5\u2009\u00b1\u20096.7 months (range 45\u201371 months) and the 5-year survival rate was 53%. We found that a statistically significant correlation between lymph node metastasis in N1 or N2 stations and survival. There was also a significant relationship between N2 nodal metastasis and recurrence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>As stated in the current guidelines, lung lobectomy and mediastinal lymph node resection should be considered in early-stage small-cell lung cancers. Survival outcomes of surgery for early-stage small-cell lung cancer are similar to the results in non-small-cell lung cancer.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0218492319826724","type":"journal-article","created":{"date-parts":[[2019,1,19]],"date-time":"2019-01-19T11:14:52Z","timestamp":1547896492000},"page":"187-191","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Surgical outcomes of early-stage small-cell lung cancer: single-center experience"],"prefix":"10.1177","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5402-9031","authenticated-orcid":false,"given":"Muhammet","family":"Sayan","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery, Gazi University Faculty of Medicine, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Merve","family":"Satir Turk","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Gazi University Faculty of Medicine, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Celik","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Gazi University Faculty of Medicine, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ismail","family":"Cuneyt Kurul","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Gazi University Faculty of Medicine, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdullah","family":"Irfan Tastepe","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Gazi University Faculty of Medicine, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,1,19]]},"reference":[{"key":"bibr1-0218492319826724","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.04.4859"},{"key":"bibr2-0218492319826724","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2010.06.003"},{"key":"bibr3-0218492319826724","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2017.07.009"},{"key":"bibr4-0218492319826724","unstructured":"Small Cell Lung Cancer Clinical Practice Guidelines in Oncology (version 2. 2018). National Comprehensive Cancer Network, Inc. Available at: https:\/\/www.nccn.org. 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