{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T12:18:13Z","timestamp":1777551493127,"version":"3.51.4"},"reference-count":6,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2020,1,14]],"date-time":"2020-01-14T00:00:00Z","timestamp":1578960000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Asian Cardiovasc Thorac Ann"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:p>Patent foramen ovale, sometimes associated with clinical manifestation, is frequently detected during adulthood. Platypnea-orthodeoxia syndrome, a rare condition characterized by dyspnea and hypoxia aggravated in the upright position, is caused by a right-to-left shunt across a patent foramen ovale. We present a case of a 73-year-old man with severe hypoxia caused by an aortic arch aneurysm that distorted the atrial septal geometry and worsened the right-to-left shunt. Clinicians should consider a right-to-left shunt via a patent foramen ovale when an aortic arch aneurysm causes counterclockwise cardiac rotation. Furthermore, the alveolar-arterial oxygen difference can be used to diagnose platypnea-orthodeoxia syndrome.<\/jats:p>","DOI":"10.1177\/0218492320901924","type":"journal-article","created":{"date-parts":[[2020,1,14]],"date-time":"2020-01-14T21:55:17Z","timestamp":1579038917000},"page":"172-174","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Severe hypoxia caused by ascending aorta elongation due to aortic arch aneurysm"],"prefix":"10.1177","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6084-8669","authenticated-orcid":false,"given":"Masaaki","family":"Naganuma","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, Aomori Prefectural Central Hospital, Aomori, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kota","family":"Itagaki","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Aomori Prefectural Central Hospital, Aomori, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuaki","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Aomori Prefectural Central Hospital, Aomori, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3184-7509","authenticated-orcid":false,"given":"Shinya","family":"Masuda","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Aomori Prefectural Central Hospital, Aomori, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koichi","family":"Nagaya","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Aomori Prefectural Central Hospital, Aomori, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,1,14]]},"reference":[{"key":"bibr1-0218492320901924","doi-asserted-by":"publisher","DOI":"10.3390\/jcm5100085"},{"key":"bibr2-0218492320901924","first-page":"563","volume":"159","author":"Burchell HB","year":"1949","journal-title":"Am J Physiol"},{"key":"bibr3-0218492320901924","doi-asserted-by":"publisher","DOI":"10.1378\/chest.107.6.1504"},{"key":"bibr4-0218492320901924","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2003.027839"},{"key":"bibr5-0218492320901924","doi-asserted-by":"publisher","DOI":"10.1016\/0003-4975(96)00386-4"},{"key":"bibr6-0218492320901924","doi-asserted-by":"publisher","DOI":"10.1253\/circj.70.1611"}],"container-title":["Asian Cardiovascular and Thoracic Annals"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0218492320901924","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0218492320901924","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0218492320901924","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T17:54:42Z","timestamp":1777398882000},"score":1,"resource":{"primary":{"URL":"http:\/\/journals.sagepub.com\/doi\/10.1177\/0218492320901924"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,14]]},"references-count":6,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,3]]}},"alternative-id":["10.1177\/0218492320901924"],"URL":"https:\/\/doi.org\/10.1177\/0218492320901924","relation":{},"ISSN":["0218-4923","1816-5370"],"issn-type":[{"value":"0218-4923","type":"print"},{"value":"1816-5370","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,14]]}}}