{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T19:12:38Z","timestamp":1777576358365,"version":"3.51.4"},"reference-count":7,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2021,7,5]],"date-time":"2021-07-05T00:00:00Z","timestamp":1625443200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Asian Cardiovasc Thorac Ann"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:p>Outflow cannula occlusion is an infrequent complication occurring among recipients of continuous flow left ventricular assist devices. Hereby, we present a case of a 66-year-old man with a HeartMate 3 left ventricular assist device that presented 18 months after implantation and during his admission, evidence of poor left ventricular unloading and forward flow uncovered intrinsic and extrinsic outflow cannula obstruction. The patient\u2019s course was complicated by cardiogenic shock, diffuse alveolar hemorrhage and multiorgan failure. Post-mortem examination suggested foreign body reaction as a potential contributor of outflow graft obstruction at the level of the bend relief.<\/jats:p>","DOI":"10.1177\/02184923211031343","type":"journal-article","created":{"date-parts":[[2021,7,6]],"date-time":"2021-07-06T00:56:30Z","timestamp":1625532990000},"page":"596-600","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Outflow graft foreign body reaction and thrombosis in HeartMate 3 left ventricular assist device"],"prefix":"10.1177","volume":"30","author":[{"given":"Paulino","family":"Alvarez","sequence":"first","affiliation":[{"name":"Section of Heart Failure and Transplantation, Department of Cardiovascular Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Humble","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dennis","family":"Firchau","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5740-9670","authenticated-orcid":false,"given":"Alexandros","family":"Briasoulis","sequence":"additional","affiliation":[{"name":"Section of Heart Failure and Transplantation, Department of Cardiovascular Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,7,5]]},"reference":[{"key":"bibr1-02184923211031343","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1900486"},{"key":"bibr2-02184923211031343","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.117.028303"},{"key":"bibr3-02184923211031343","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2018.08.011"},{"key":"bibr4-02184923211031343","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.117.004275"},{"key":"bibr5-02184923211031343","doi-asserted-by":"publisher","DOI":"10.1016\/j.carpath.2019.107156"},{"key":"bibr6-02184923211031343","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.114.001891"},{"key":"bibr7-02184923211031343","doi-asserted-by":"publisher","DOI":"10.1093\/icvts\/ivu227"}],"container-title":["Asian Cardiovascular and Thoracic Annals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02184923211031343","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/02184923211031343","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02184923211031343","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T19:28:00Z","timestamp":1777404480000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/02184923211031343"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,5]]},"references-count":7,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["10.1177\/02184923211031343"],"URL":"https:\/\/doi.org\/10.1177\/02184923211031343","relation":{},"ISSN":["0218-4923","1816-5370"],"issn-type":[{"value":"0218-4923","type":"print"},{"value":"1816-5370","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7,5]]}}}