{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T19:12:19Z","timestamp":1777576339717,"version":"3.51.4"},"reference-count":11,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2021,10,4]],"date-time":"2021-10-04T00:00:00Z","timestamp":1633305600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Asian Cardiovasc Thorac Ann"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:p>We report a very rare case of cT1N0M0 lung adenocarcinoma reveling Lambert-Eaton myasthenic syndrome (LEMS). A 69-year-old nonsmoking woman, with several comorbidities consulted for cough and dyspnea. Chest radiograph and CT scanning detected a left lower lobe mass; Needle biopsy confirmed differentiated adenocarcinoma; 18FDG-PET scan and Brain MRI eliminated metastatic disease dissemination. Our patient underwent a left lower lobectomy with mediastinal lymphadenectomy (pT1N0M0), no adjuvant chemotherapy was administrated. One month later patient present a muscle weakness in both lower limbs and fatigability followed by an inability to walk. The diagnosis of LEMS was made from the distinctive electromyogram (EMG) findings and a treatment with Amifampridine (3, 4-diaminopyridine phosphate [3, 4-DAP]) was prescribed with evident efficacy for symptoms.<\/jats:p>","DOI":"10.1177\/02184923211051796","type":"journal-article","created":{"date-parts":[[2021,10,4]],"date-time":"2021-10-04T12:36:04Z","timestamp":1633350964000},"page":"490-492","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Lambert\u2013Eaton myasthenic syndrome revealed after surgery of lung adenocarcinoma"],"prefix":"10.1177","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5514-8983","authenticated-orcid":false,"given":"El Hassane","family":"Kabiri","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery, Department of Medical Oncology, Mohammed V Military Teaching Hospital, Rabat Morocco"},{"name":"Facult\u00e9 de M\u00e9decine et de Pharmacie, Universit\u00e9 Mohammed V, Rabat Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6892-8444","authenticated-orcid":false,"given":"Massine El","family":"Hammoumi","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Department of Medical Oncology, Mohammed V Military Teaching Hospital, Rabat Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yassir","family":"Sbitti","sequence":"additional","affiliation":[{"name":"Facult\u00e9 de M\u00e9decine et de Pharmacie, Universit\u00e9 Mohammed V, Rabat Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,10,4]]},"reference":[{"key":"bibr1-02184923211051796","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2015.3473"},{"key":"bibr2-02184923211051796","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000006484"},{"key":"bibr3-02184923211051796","doi-asserted-by":"publisher","DOI":"10.1177\/2324709617721251"},{"key":"bibr4-02184923211051796","doi-asserted-by":"publisher","DOI":"10.1111\/1759-7714.13385"},{"key":"bibr5-02184923211051796","doi-asserted-by":"publisher","DOI":"10.1111\/imj.14128"},{"key":"bibr6-02184923211051796","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-019-04139-0"},{"key":"bibr7-02184923211051796","doi-asserted-by":"publisher","DOI":"10.1016\/j.ncl.2018.01.008"},{"key":"bibr8-02184923211051796","doi-asserted-by":"publisher","DOI":"10.1186\/1752-1947-6-281"},{"key":"bibr9-02184923211051796","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1957.02970480021005"},{"key":"bibr10-02184923211051796","doi-asserted-by":"publisher","DOI":"10.1358\/dot.2020.56.10.3137144"},{"key":"bibr11-02184923211051796","doi-asserted-by":"publisher","DOI":"10.1177\/1060028019864574"}],"container-title":["Asian Cardiovascular and Thoracic Annals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02184923211051796","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/02184923211051796","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02184923211051796","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T19:27:57Z","timestamp":1777404477000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/02184923211051796"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,4]]},"references-count":11,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["10.1177\/02184923211051796"],"URL":"https:\/\/doi.org\/10.1177\/02184923211051796","relation":{},"ISSN":["0218-4923","1816-5370"],"issn-type":[{"value":"0218-4923","type":"print"},{"value":"1816-5370","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10,4]]}}}