{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T19:14:53Z","timestamp":1777576493045,"version":"3.51.4"},"reference-count":18,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Asian Cardiovasc Thorac Ann"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>To reduce surgical stress, we omit mediastinal lymph node dissection (MLND) in patients with non-small cell lung cancer aged \u226580 years without N1 metastasis, as confirmed via surgery. This study examined the effect of MLND omission on prognosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Altogether, 212 eligible patients with clinical N0 non-small cell lung cancer underwent video-assisted thoracoscopic lobectomy between 2007 and 2017. Patients were classified into two groups as follows: patients aged 75\u201379 years who underwent MLND group, and patients aged \u226580 years in whom MLND was omitted (non-MLND group). Propensity score matching was performed between the two groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>There were 86 patients after matching. The non-MLND group showed shorter operative time (237.5\u2005min vs. 207.5\u2005min, p\u2009\u2009=\u2009\u20090.018). No differences in postoperative complications were noted between the two groups. Between the MLND group and non-MLND group, the 5-year overall survival rates were 84.0% and 84.7% ( p\u2009\u2009=\u2009\u20090.989), relapse-free survival rates were 69.8% and 74.7% ( p\u2009\u2009=\u2009\u20090.855), and cancer-specific survival rates were 91.4% and 91.6% ( p\u2009\u2009=\u2009\u20090.700), respectively. These results did not differ significantly.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study demonstrated that MLND does not affect the prognosis of patients with non-small cell lung cancer aged \u226580 years. Lobectomy without MLND is one of the surgical treatment options in older patients with clinical N0 non-small cell lung cancer. Naturally, the clinical stage of patients must be carefully evaluated before surgery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/02184923231180778","type":"journal-article","created":{"date-parts":[[2023,6,9]],"date-time":"2023-06-09T02:50:02Z","timestamp":1686279002000},"page":"431-438","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Treatment outcomes of lobectomy with and without mediastinal lymph node dissection in older patients with clinical N0 non-small cell lung cancer"],"prefix":"10.1177","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2867-2274","authenticated-orcid":false,"given":"Tomohiro","family":"Fujita","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery, National Hospital Organization Hamada Medical Center, Shimane, Japan"},{"name":"Department of Thoracic Surgery, Shimane University Hospital, Shimane, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Koyanagi","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Shimane University Hospital, Shimane, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koji","family":"Kishimoto","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Shimane University Hospital, Shimane, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,6,8]]},"reference":[{"key":"bibr1-02184923231180778","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(19)42606-8"},{"key":"bibr2-02184923231180778","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2010.11.008"},{"key":"bibr3-02184923231180778","doi-asserted-by":"publisher","DOI":"10.1510\/icvts.2008.193383"},{"key":"bibr4-02184923231180778","doi-asserted-by":"publisher","DOI":"10.1007\/s00595-021-02373-8"},{"key":"bibr5-02184923231180778","unstructured":"UICC International Union Against Cancer. TNM Classification of Malignant Tumours: Lung and Pleural Tumors. 2009. http:\/\/www.inen.sld.pe\/portal\/documentos\/pdf\/educacion\/13072015_TNM%20-Classification.pdf. (Accessed 27 November 2022)."},{"key":"bibr6-02184923231180778","doi-asserted-by":"publisher","DOI":"10.1097\/00000421-198212000-00014"},{"key":"bibr7-02184923231180778","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000133083.54934.ae"},{"key":"bibr8-02184923231180778","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(87)90171-8"},{"key":"bibr9-02184923231180778","doi-asserted-by":"publisher","DOI":"10.1038\/bmt.2012.244"},{"key":"bibr10-02184923231180778","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2007.10.057"},{"key":"bibr11-02184923231180778","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezx437"},{"key":"bibr12-02184923231180778","doi-asserted-by":"publisher","DOI":"10.1097\/JTO.0b013e3181ae285d"},{"key":"bibr13-02184923231180778","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2005.06.066"},{"key":"bibr14-02184923231180778","doi-asserted-by":"publisher","DOI":"10.1007\/s11748-012-0086-3"},{"key":"bibr15-02184923231180778","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d4013"},{"key":"bibr16-02184923231180778","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdv008"},{"key":"bibr17-02184923231180778","doi-asserted-by":"publisher","DOI":"10.1177\/107327480701400108"},{"key":"bibr18-02184923231180778","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2012.08.075"}],"container-title":["Asian Cardiovascular and Thoracic Annals"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02184923231180778","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/02184923231180778","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02184923231180778","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T19:28:28Z","timestamp":1777404508000},"score":1,"resource":{"primary":{"URL":"http:\/\/journals.sagepub.com\/doi\/10.1177\/02184923231180778"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":18,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["10.1177\/02184923231180778"],"URL":"https:\/\/doi.org\/10.1177\/02184923231180778","relation":{},"ISSN":["0218-4923","1816-5370"],"issn-type":[{"value":"0218-4923","type":"print"},{"value":"1816-5370","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6]]}}}