{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T19:15:14Z","timestamp":1777576514643,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Asian Cardiovasc Thorac Ann"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Optimal management of moderate aortic stenosis during surgery for another indication is unclear. We assessed the effects of surgical aortic valve replacement for moderate aortic stenosis during mitral surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>An institutional mitral surgery database was queried for patients with preoperative moderate aortic stenosis. Patients were stratified by whether they underwent concomitant surgical aortic valve replacement. Morbidity was analyzed using Student's t tests, Wilcoxon rank sum, chi-squared, and Fisher's exact tests. Survival was analyzed using Kaplan\u2013Meier estimation and Cox regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 85 mitral surgery recipients with moderate aortic stenosis from 2012 to 2019, 62 (73%) underwent concomitant surgical aortic valve replacement. Surgical aortic valve replacement recipients were more likely to have bicuspid (11% vs. 0%, p\u2009\u2009=\u2009\u20090.019) or rheumatic (18% vs. 0%, p\u2009\u2009=\u2009\u20090.019) aortic valves, and to undergo mitral repair (32% vs. 9%, p\u2009\u2009=\u2009\u20090.028). Groups did not differ with respect to mitral etiology, New York Heart Association class, or cardiac intervention history ( p\u2009&gt;\u20090.05). Postoperatively, groups had similar stroke and gastrointestinal bleed rates (3% vs. 0% and 2% vs. 0% in the surgical aortic valve replacement vs. no surgical aortic valve replacement group respectively, both p\u2009&gt;\u20090.99). Five-year survival free from severe aortic stenosis was higher in the surgical aortic valve replacement group (66% vs. 17%, p\u2009\u2009=\u2009\u20090.002). Surgical aortic valve replacement protected against the composite of death and progression to severe aortic stenosis at 5 years (hazard ratio: 0.32, p\u2009\u2009=\u2009\u20090.003).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Surgical aortic valve replacement for moderate aortic stenosis at time of mitral surgery is a well-tolerated strategy to reduce aortic disease progression.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/02184923231186850","type":"journal-article","created":{"date-parts":[[2023,7,7]],"date-time":"2023-07-07T03:14:35Z","timestamp":1688699675000},"page":"475-482","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Aortic valve replacement for moderate aortic stenosis during mitral surgery improves survival free from severe stenosis"],"prefix":"10.1177","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3813-7355","authenticated-orcid":false,"given":"Noah","family":"Weingarten","sequence":"first","affiliation":[{"name":"Division of Cardiovascular Surgery, Department of Surgery, University of Pennsylvania, Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Rekhtman","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery, Department of Surgery, University of Pennsylvania, Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amit","family":"Iyengar","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery, Department of Surgery, University of Pennsylvania, Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8538-6085","authenticated-orcid":false,"given":"Cindy","family":"Song","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery, Department of Surgery, University of Pennsylvania, Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mrinal","family":"Patel","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery, Department of Surgery, University of Pennsylvania, Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pavan","family":"Atluri","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery, Department of Surgery, University of Pennsylvania, Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,7,7]]},"reference":[{"key":"bibr1-02184923231186850","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.05.015"},{"key":"bibr2-02184923231186850","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.121.057639"},{"key":"bibr3-02184923231186850","first-page":"e72","volume":"143","author":"Otto CM","year":"2021","journal-title":"Circulation"},{"key":"bibr4-02184923231186850","doi-asserted-by":"publisher","DOI":"10.1016\/j.rec.2022.05.006"},{"key":"bibr5-02184923231186850","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2015.08.016"},{"key":"bibr6-02184923231186850","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2010.11.009"},{"key":"bibr7-02184923231186850","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2010.06.036"},{"key":"bibr8-02184923231186850","doi-asserted-by":"publisher","DOI":"10.15420\/icr.2021.04"},{"key":"bibr9-02184923231186850","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jew335"},{"key":"bibr10-02184923231186850","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2009.07.013"},{"key":"bibr11-02184923231186850","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1016\/j.athoracsur.2018.03.003","volume":"105","author":"O\u2019Brien SM","year":"2018","journal-title":"Ann Thorac 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