{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T16:27:32Z","timestamp":1781627252605,"version":"3.54.5"},"reference-count":13,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T00:00:00Z","timestamp":1692921600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Asian Cardiovasc Thorac Ann"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>There are limited studies reporting follow-up outcome data comparing of off-pump coronary artery bypass (OPCAB) with on-pump (ONCAB) technique. The aim of the study was to report the 5-year clinical outcomes of OPCAB and ONCAB in a post hoc analysis of the PROMOTE patency trial.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>From March 2016 through March 2017, a total of 321 patients undergoing coronary artery bypass grafting (CABG) were randomised to either the off-pump or the on-pump technique. Data on all-cause mortality, myocardial infarction (MI), cerebrovascular accident (CVA), repeat revascularisation and need for renal replacement therapy (RRT) were recorded. The composite and each of these individual outcomes are reported at 5-year interval.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The mean follow-up period was 65.9 months (\u00b13.39). A total of 275 (85.93%) patients followed up at the 5-year interval who underwent CABG by the off-pump ( n\u2009\u2009=\u2009\u2009158) and the on-pump ( n\u2009\u2009=\u2009\u2009162) technique. The all-cause mortality was 8.9% and 5.7% in ONCAB and OPCAB, respectively (hazard ratio [HR]\u2009\u2009=\u2009\u20090.62; 95% confidence interval [CI] 0.25\u20131.57, p\u2009\u2009=\u2009\u20090.31). The composite of all-cause mortality, non-fatal MI, non-fatal CVA, RRT and need for repeat revascularisation was comparable in both groups (7.1% vs. 11.9%, HR\u2009\u2009=\u2009\u20090.57; 95% CI 0.25\u20131.31, p\u2009\u2009=\u2009\u20090.18 in OPCAB and ONCAB, respectively). The rates of 5-year non-fatal MI ( p\u2009\u2009=\u2009\u20090.2), non-fatal CVA ( p\u2009\u2009=\u2009\u20090.36) and need for repeat revascularisation ( p\u2009\u2009=\u2009\u20091) were similar in both groups. A sub-group analysis did not show any significant interaction or effect modification with either of the techniques.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The 5-year clinical outcomes of OPCAB are comparable to ONCAB in low-risk patients undergoing CABG. Off-pump coronary artery bypass had no additional benefit in any subgroup.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/02184923231197642","type":"journal-article","created":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T12:02:17Z","timestamp":1692964937000},"page":"659-666","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Five-year outcomes of off and on-pump CABG: Insights from PROMOTE Patency Trial"],"prefix":"10.1177","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0842-7458","authenticated-orcid":false,"given":"Lokeswara Rao","family":"Sajja","sequence":"first","affiliation":[{"name":"Division of Cardiothoracic Surgery, Star Hospitals, Hyderabad, India"},{"name":"Division of Clinical Research in Cardiovascular Medicine\/Surgery, Sajja Heart Foundation, Hyderabad, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kunal","family":"Sarkar","sequence":"additional","affiliation":[{"name":"Division of Cardiothoracic Surgery, Medica Superspeciality Hospital, Kolkata, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gopichand","family":"Mannam","sequence":"additional","affiliation":[{"name":"Division of Cardiothoracic Surgery, Star Hospitals, Hyderabad, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chandrasekhar","family":"Padmanabhan","sequence":"additional","affiliation":[{"name":"Division of Cardiothoracic Surgery, G Kuppuswamy Naidu Memorial Hospital, Coimbatore, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3843-1338","authenticated-orcid":false,"given":"Pradeep","family":"Narayan","sequence":"additional","affiliation":[{"name":"Division of Cardiothoracic Surgery, Rabindranath Tagore International Institute of Cardiac Sciences, Kolkata, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Devanish NH","family":"Kamtam","sequence":"additional","affiliation":[{"name":"Division of Clinical Research in Cardiovascular Medicine\/Surgery, Sajja Heart Foundation, Hyderabad, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5613-0942","authenticated-orcid":false,"given":"Nagalla","family":"Balakrishna","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Sajja Heart Foundation, Hyderabad, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Venkata Krishna Kumar","family":"Kodali","sequence":"additional","affiliation":[{"name":"Division of Cardiothoracic Surgery, Krishna Institute of Medical Sciences, Secunderabad, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anvay","family":"Mulay","sequence":"additional","affiliation":[{"name":"Division of Cardiothoracic Surgery, Sir H. N. Reliance Foundation Hospital and Research Centre, Mumbai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjeeth","family":"Peter","sequence":"additional","affiliation":[{"name":"Division of Cardiothoracic Surgery, DDMM Heart Institute, Nadiad, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prashanthi","family":"Beri","sequence":"additional","affiliation":[{"name":"Division of Clinical Research in Cardiovascular Medicine\/Surgery, Sajja Heart Foundation, Hyderabad, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,8,25]]},"reference":[{"key":"bibr1-02184923231197642","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1614341"},{"key":"bibr2-02184923231197642","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1601564"},{"key":"bibr3-02184923231197642","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.924258"},{"key":"bibr4-02184923231197642","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2017.10.135"},{"key":"bibr5-02184923231197642","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.118.035857"},{"key":"bibr6-02184923231197642","doi-asserted-by":"publisher","DOI":"10.1007\/s12055-019-00869-0"},{"key":"bibr7-02184923231197642","doi-asserted-by":"publisher","DOI":"10.1007\/s12055-020-00940-1"},{"key":"bibr8-02184923231197642","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2006.09.028"},{"key":"bibr9-02184923231197642","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.119.039584"},{"key":"bibr10-02184923231197642","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezv170"},{"key":"bibr11-02184923231197642","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2016.06.038"},{"key":"bibr12-02184923231197642","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2013.10.045"},{"key":"bibr13-02184923231197642","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2020.02.035"}],"container-title":["Asian Cardiovascular and Thoracic Annals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02184923231197642","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/02184923231197642","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02184923231197642","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T19:28:33Z","timestamp":1777404513000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/02184923231197642"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,25]]},"references-count":13,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2023,10]]}},"alternative-id":["10.1177\/02184923231197642"],"URL":"https:\/\/doi.org\/10.1177\/02184923231197642","relation":{},"ISSN":["0218-4923","1816-5370"],"issn-type":[{"value":"0218-4923","type":"print"},{"value":"1816-5370","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,25]]}}}