{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T10:02:53Z","timestamp":1780135373186,"version":"3.54.0"},"reference-count":6,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:00:00Z","timestamp":1777852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Asian Cardiovasc Thorac Ann"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Traumatic major limb amputations require urgent intervention to prevent irreversible tissue necrosis and life-threatening systemic complications due to warm ischemia. We aim to demonstrate the efficacy of extracorporeal circulation (ECC) in extending the ischemia tolerance window and stabilizing metabolic parameters during multidisciplinary replantation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation<\/jats:title>\n                    <jats:p>A 23-year-old female presented with bilateral total upper extremity amputations following a high-energy motor vehicle accident. While damage control surgery addressed intra-abdominal injuries, the amputated limbs were preserved using a neonatal oxygenator and a specialized ECC circuit. Perfusion was maintained for 224 minutes, achieving significant metabolic stabilization, with arterial pH improving from 6.72 to 7.57.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Although the right limb required secondary amputation due to the initial crush injury, the left limb was successfully salvaged. At the 3-year follow-up, the patient exhibited excellent functional recovery with restored motor and sensory functions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>ECC is a vital modality in complex trauma management, providing a metabolic bridge to replantation and improving long-term clinical outcomes in major limb salvage.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/02184923261446677","type":"journal-article","created":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T15:06:44Z","timestamp":1777907204000},"page":"461-464","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Use of extracorporeal circulation in multidisciplinary approach and replantation strategies for traumatic limb amputations: A case report"],"prefix":"10.1177","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-8427-3775","authenticated-orcid":false,"given":"Hasan","family":"Bayram","sequence":"first","affiliation":[{"name":"Kocaeli University Faculty of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5116-4361","authenticated-orcid":false,"given":"Aysegul","family":"Durmaz","sequence":"additional","affiliation":[{"name":"Kocaeli University Faculty of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9599-1577","authenticated-orcid":false,"given":"Ali Ahmet","family":"Arikan","sequence":"additional","affiliation":[{"name":"Kocaeli University Faculty of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sadan","family":"Yavuz","sequence":"additional","affiliation":[{"name":"Kocaeli University Faculty of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,5,4]]},"reference":[{"key":"e_1_3_2_2_2","first-page":"115","article-title":"Replantation of the upper extremity","volume":"71","author":"Manske PR","year":"1982","unstructured":"Manske PR. Replantation of the upper extremity. Postgrad Med 1982; 71: 115\u2013122.","journal-title":"Postgrad Med"},{"key":"e_1_3_2_3_2","first-page":"312","article-title":"Replantation of the upper limb","volume":"44","author":"Sabapathy SR","year":"2011","unstructured":"Sabapathy SR, Venkatramani H, Bhardwaj P. Replantation of the upper limb. Indian J Plast Surg 2011; 44: 312\u2013319.","journal-title":"Indian J Plast Surg"},{"key":"e_1_3_2_4_2","article-title":"The \u201cRule of Nines\u201d and total cardiac output distribution","volume":"70","author":"Knapik JJ","year":"2011","unstructured":"Knapik JJ, et al. The \u201cRule of Nines\u201d and total cardiac output distribution. J Trauma 2011; 70: E55.","journal-title":"J Trauma"},{"key":"e_1_3_2_5_2","first-page":"1","article-title":"Replantation and revascularization","volume":"15","author":"Atasoy E","year":"1998","unstructured":"Atasoy E. Replantation and revascularization. Methods Plast Surg 1998; 15: 1\u201324.","journal-title":"Methods Plast Surg"},{"key":"e_1_3_2_6_2","first-page":"1393","article-title":"Replantation of a completely Eastern limb: a case report","volume":"61","author":"Basheer MH","year":"2008","unstructured":"Basheer MH, et al. Replantation of a completely Eastern limb: a case report. J Plast Reconstr Aesthet Surg 2008; 61: 1393\u20131397.","journal-title":"J Plast Reconstr Aesthet Surg"},{"key":"e_1_3_2_7_2","first-page":"455","article-title":"Extracorporeal membrane oxygenation in the management of major limb trauma","volume":"29","author":"Constantinides J","year":"2014","unstructured":"Constantinides J, et al. Extracorporeal membrane oxygenation in the management of major limb trauma. Perfusion 2014; 29: 455\u2013458.","journal-title":"Perfusion"}],"container-title":["Asian Cardiovascular and Thoracic Annals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02184923261446677","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/02184923261446677","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02184923261446677","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T09:50:26Z","timestamp":1780134626000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/02184923261446677"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,4]]},"references-count":6,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["10.1177\/02184923261446677"],"URL":"https:\/\/doi.org\/10.1177\/02184923261446677","relation":{},"ISSN":["0218-4923","1816-5370"],"issn-type":[{"value":"0218-4923","type":"print"},{"value":"1816-5370","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,4]]}}}