{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T17:27:07Z","timestamp":1777915627896,"version":"3.51.4"},"reference-count":76,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2021,5,7]],"date-time":"2021-05-07T00:00:00Z","timestamp":1620345600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00ecvel Superior","doi-asserted-by":"publisher","award":["scholarship for ACLR"],"award-info":[{"award-number":["scholarship for ACLR"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Nutr Health"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Psoriasis is a chronic, immune-mediated skin disease. It affects skin and joints, characterized by abnormal hyperproliferation of keratinocytes. The worldwide prevalence of psoriasis ranges from 2% to 4%. Environmental factors as smoking, alcohol consumption obesity can also work as triggers. During the inflammatory process, there is an exacerbated formation of free radicals and antioxidants are required to maintain redox balance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>Assess antioxidant profiles.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A cross-sectional study was conducted between August\/2012 and March\/2014. Sociodemographic, lifestyle, and biochemical measurements, dietary intake, serum lycopene and \u03b1-tocopherol, psoriasis severity according to Psoriasis Area and Severity Index were obtained. Comparisons between serum lycopene and \u03b1-tocopherol distributions according to variables were conducted using a one-way analysis of variance. Multiple linear regression was used to investigate factors associated with serum antioxidants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>81 participants (56% female, 62% non-white), 34% without psoriatic lesions, 51% diagnosed with mild psoriasis, and 15% with moderate psoriasis. Median (IQR) age of 54 (41, 62) years, 10 (4, 11) years of education, 17% smokers, 46% overweight and 25% obesity. In total, 72% did not reach the daily recommendation of fruit and vegetable intake. Serum lycopene and \u03b1-tocopherol were 0.2 (0.1\u20130.3) \u00b5mol\/L and 22.5 (18.5\u201325.6) \u00b5mol\/L, respectively. Only 14% presented adequate concentration of lycopene, but adequate \u03b1-tocopherol level was observed among 88%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Patients reported a diet low in vegetables and fruits and rich in ultra-processed foods and fatty acids. Adequate circulating \u03b1-tocopherol but low serum lycopene, was observed among patients. A linear trend was observed for lycopene according to the severity of psoriasis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/02601060211014127","type":"journal-article","created":{"date-parts":[[2021,5,9]],"date-time":"2021-05-09T03:48:49Z","timestamp":1620532129000},"page":"239-248","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Low serum lycopene, and adequate \u03b1-tocopherol levels in patients with psoriasis: A cross-sectional study"],"prefix":"10.1177","volume":"28","author":[{"given":"Ana C L","family":"Rocha","sequence":"first","affiliation":[{"name":"Departament of Preventive Medicine, Universidade Federal de S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria C","family":"Bortoletto","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina do ABC, Santo Andr\u00e9, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e9ia C","family":"da Costa","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina do ABC, Santo Andr\u00e9, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luiza K M","family":"Oyafuso","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina do ABC, Santo Andr\u00e9, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adriana","family":"Sanudo","sequence":"additional","affiliation":[{"name":"Departament of Preventive Medicine, Universidade Federal de S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9652-038X","authenticated-orcid":false,"given":"Luciana Y","family":"Tomita","sequence":"additional","affiliation":[{"name":"Departament of Preventive Medicine, Universidade Federal de S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,5,7]]},"reference":[{"key":"bibr1-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1016\/j.dsi.2013.02.001"},{"key":"bibr2-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1016\/j.jand.2012.02.006"},{"key":"bibr3-02601060211014127","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph13070743"},{"key":"bibr4-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2010.04844.x"},{"key":"bibr5-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0074558"},{"key":"bibr6-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a116965"},{"key":"bibr7-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.201100222"},{"key":"bibr8-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2019.02.038"},{"issue":"3","key":"bibr9-02601060211014127","volume":"56","author":"Calder PC","year":"2002","journal-title":"European Journal of Clinical Nutrition"},{"key":"bibr10-02601060211014127","author":"Carrascosa JM","year":"2014","journal-title":"Actas Dermo-Sifiliogr\u00e1ficas (English Edition)"},{"key":"bibr11-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1590\/S0365-05962010000300009"},{"key":"bibr12-02601060211014127","author":"Esposito K","year":"2013","journal-title":"New England Journal of Medicine"},{"key":"bibr13-02601060211014127","doi-asserted-by":"publisher","DOI":"10.4061\/2011\/293916"},{"key":"bibr14-02601060211014127","doi-asserted-by":"publisher","DOI":"10.3109\/09637486.2016.1147020"},{"key":"bibr15-02601060211014127","volume-title":"Human Vitamin and Energy Requirements","author":"FAO\/WHO\/UNU Expert Consultation","year":"2001"},{"key":"bibr16-02601060211014127","volume-title":"Human Energy Requirements","author":"FAO\/WHO\/UNU Expert Consultation","year":"2004"},{"key":"bibr17-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1990.tb04192.x"},{"key":"bibr18-02601060211014127","volume":"360","author":"Fiolet T","year":"2018","journal-title":"BMJ (Online)"},{"key":"bibr19-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2018.1412"},{"key":"bibr20-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2012.943"},{"key":"bibr21-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1590\/s1679-45082010ao1499"},{"key":"bibr22-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1089\/152308604322899305"},{"issue":"1","key":"bibr23-02601060211014127","first-page":"S72","volume":"24","author":"Griffiths CE","year":"2006","journal-title":"Clinical and Experimental Rheumatology"},{"key":"bibr24-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2013.09.010"},{"key":"bibr25-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.143.12.1559"},{"key":"bibr26-02601060211014127","unstructured":"Institute for Health Metrics and Evaluation (2012) Global burden of disease study 2010: results by cause 1990\u20132010. Seattle: Institute for Health Metrics and Evaluation."},{"key":"bibr27-02601060211014127","volume-title":"Dietary Reference Intakes","author":"Institute of Medicine","year":"2005"},{"key":"bibr28-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1093\/advances\/nmy040"},{"key":"bibr29-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2014.03.035"},{"key":"bibr30-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1016\/j.jand.2012.03.029"},{"key":"bibr31-02601060211014127","volume-title":"Carbohydrates in Human Nutrition","author":"Joint FAO\/WHO Expert Consultation","year":"1997"},{"key":"bibr32-02601060211014127","volume-title":"Diet, Nutrition and the Prevention of Chronic Diseases","author":"Joint WHO\/FAO Expert Consultation on diet, nutrition and the prevention of chronic diseases","year":"2002"},{"key":"bibr33-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2014.183"},{"issue":"4","key":"bibr34-02601060211014127","volume":"159","author":"Kaye JA","year":"2008","journal-title":"Bristih Journal of Dermatology"},{"key":"bibr35-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1097\/PSY.0b013e3181dbf489"},{"key":"bibr36-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiochem.2015.06.023"},{"key":"bibr37-02601060211014127","volume-title":"Applied Regression Analysis and Other Multivariable Methods","author":"Kleinbaum DG","year":"2008"},{"key":"bibr76-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD011972.pub2"},{"key":"bibr38-02601060211014127","unstructured":"Krueger G, Koo J, Lebwohl M, et al. (2001) The impact of psoriasis on quality of life: results of a 1998 National Psoriasis Foundation patient-membership survey. Archives of Dermatology 137(3): 280\u2013284. Available at: http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/11255325."},{"issue":"2","key":"bibr39-02601060211014127","first-page":"ii18","volume":"64","author":"Langley RG","year":"2005","journal-title":"Ann Rheum Dis"},{"key":"bibr40-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-012-9911-3"},{"key":"bibr41-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.23811"},{"key":"bibr42-02601060211014127","doi-asserted-by":"publisher","DOI":"10.3109\/10715762.2016.1162301"},{"key":"bibr43-02601060211014127","author":"Martins GA","journal-title":"Anais Brasileiros de\u00a0Dermatologia"},{"key":"bibr44-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1111\/bph.13625"},{"key":"bibr45-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1017\/S1368980017001379"},{"key":"bibr46-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1017\/S1368980017000234"},{"key":"bibr47-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1080\/10408398.2013.801827"},{"key":"bibr48-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2009.315"},{"key":"bibr49-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1996.tb03826.x"},{"key":"bibr50-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2016-312016"},{"key":"bibr51-02601060211014127","unstructured":"Pan American Health Organization (2001) Encuesta Multicentrica salud bienestar y envejecimiento (SABE) em America Latina el Caribe: informe preliminar. Caribe. Available at: www.opas.org\/program\/sabe.html (accessed 27 April 2021)."},{"key":"bibr52-02601060211014127","author":"Pennant M","year":"2013","journal-title":"British Journal of Nutrition"},{"key":"bibr53-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2018.2127"},{"key":"bibr54-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2010.204"},{"key":"bibr55-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1590\/S1415-52732002000200012"},{"key":"bibr56-02601060211014127","doi-asserted-by":"publisher","DOI":"10.5751\/ES-03180-140232"},{"key":"bibr57-02601060211014127","doi-asserted-by":"publisher","DOI":"10.3945\/jn.115.218487"},{"key":"bibr58-02601060211014127","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-1273"},{"key":"bibr59-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1159\/000083509"},{"key":"bibr60-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1590\/abd1806-4841.20142633"},{"key":"bibr61-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2007.06.020"},{"key":"bibr62-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1080\/07315724.2002.10719248"},{"key":"bibr63-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1159\/000366100"},{"key":"bibr64-02601060211014127","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2014.00368"},{"key":"bibr65-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1186\/1741-7015-12-77"},{"key":"bibr66-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8223(01)00078-5"},{"key":"bibr67-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1006\/abbi.1995.0019"},{"key":"bibr68-02601060211014127","unstructured":"US Department of Agriculture ARS (2014) USDA National Nutrient Database for Standard Reference, Release 27. Available at: http:\/\/www.ars.usda.gov\/ba\/bhnrc\/ndl (accessed 27 April 2021)."},{"key":"bibr69-02601060211014127","doi-asserted-by":"publisher","DOI":"10.4103\/2229-5178.164483"},{"key":"bibr70-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1017\/S1368980012005459"},{"key":"bibr71-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/26.1.224"},{"key":"bibr72-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2018.11.001"},{"key":"bibr73-02601060211014127","doi-asserted-by":"publisher","DOI":"10.17265\/2159-5313\/2016.09.003"},{"key":"bibr74-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1017\/S0029665117000325"},{"key":"bibr75-02601060211014127","doi-asserted-by":"publisher","DOI":"10.1002\/jcla.21660"}],"container-title":["Nutrition and Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02601060211014127","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/02601060211014127","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02601060211014127","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T17:25:31Z","timestamp":1777656331000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/02601060211014127"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,7]]},"references-count":76,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["10.1177\/02601060211014127"],"URL":"https:\/\/doi.org\/10.1177\/02601060211014127","relation":{},"ISSN":["0260-1060","2047-945X"],"issn-type":[{"value":"0260-1060","type":"print"},{"value":"2047-945X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,7]]}}}