{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T17:28:00Z","timestamp":1777915680094,"version":"3.51.4"},"reference-count":22,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2022,10,5]],"date-time":"2022-10-05T00:00:00Z","timestamp":1664928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Nutr Health"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>\n                    <jats:bold>Purpose:<\/jats:bold>\n                    This study aimed to evaluate the acute changes in retinal vasculature following coffee consumption.\n                    <jats:bold>Methods:<\/jats:bold>\n                    This is an interventional case series. The subjects were 22 healthy young adults. They were asked to rest in a silent room for 15\u2005min; then, their heart rate, blood pressure, and arterial oxygen saturation pressure were measured with a single patient monitoring system. Optical coherence tomography (OCT) and OCT angiography (OCT-A) imaging of the disc and macula were performed for both eyes of the subjects. These measurements were repeated 45\u2005min after drinking a cup of 450\u2005ml of coffee containing a standard dose of 130\u2005mg of caffeine. Macular and optic nerve head neurovasculature changes were assessed.\n                    <jats:bold>Results:<\/jats:bold>\n                    The results of our study did not show a significant change in peripapillary retinal nerve fiber layer thickness and neural structural and vascular parameters of the optic nerve head. Although assessments of macular vasculature showed a significant decrement in superficial (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    \u2009=\u20090.01) and deep vessel density (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    \u2009=\u20090.05) at parafovea, vessel densities (VDs) at the fovea, and deep capillary plexus at perifovea showed no significant change.\n                    <jats:bold>Conclusion<\/jats:bold>\n                    : Consuming one cup of coffee (150\u2005mg caffeine) statistically changes central foveal thickness and parafoveal blood flow but likely does not have a clinical impact in healthy young adults.\n                  <\/jats:p>","DOI":"10.1177\/02601060221130424","type":"journal-article","created":{"date-parts":[[2022,10,5]],"date-time":"2022-10-05T14:19:05Z","timestamp":1664979545000},"page":"341-347","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Acute effects of coffee consumption on the microcirculation of macula and optic nerve head"],"prefix":"10.1177","volume":"32","author":[{"given":"Nasser","family":"Shoeibi","sequence":"first","affiliation":[{"name":"Mashhad University of Medical Sciences"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Parisa","family":"Rajaei","sequence":"additional","affiliation":[{"name":"Mashhad University of Medical Sciences"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohadese","family":"Ghobadi","sequence":"additional","affiliation":[{"name":"Mashhad University of Medical Sciences"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seyedeh Maryam","family":"Hosseini","sequence":"additional","affiliation":[{"name":"Mashhad University of Medical Sciences"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mojtaba","family":"Abrishami","sequence":"additional","affiliation":[{"name":"Mashhad University of Medical Sciences"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad-Reza","family":"Ansari-Astaneh","sequence":"additional","affiliation":[{"name":"Mashhad University of Medical Sciences"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arash","family":"Omidtabrizi","sequence":"additional","affiliation":[{"name":"Mashhad University of Medical Sciences"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maryam","family":"Kadkhoda","sequence":"additional","affiliation":[{"name":"Mashhad University of Medical Sciences"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8680-5560","authenticated-orcid":false,"given":"Mehrdad Motamed","family":"Shariati","sequence":"additional","affiliation":[{"name":"Mashhad University of Medical Sciences"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,10,5]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.52.1.26"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2013.05.020"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/aos.13809"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(90)90174-P"},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.3928\/23258160-20191031-04"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0000000000001860"},{"issue":"2","key":"e_1_3_2_8_1","first-page":"103","article-title":"Symposium on glaucoma: Joint meeting with the national society for the prevention of blindness: New observations on the radial peripapillary capillaries","volume":"6","author":"Henkind P","year":"1967","unstructured":"Henkind P (1967) Symposium on glaucoma: Joint meeting with the national society for the prevention of blindness: New observations on the radial peripapillary capillaries. 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