{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T18:03:37Z","timestamp":1790877817333,"version":"4.1.0"},"reference-count":25,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T00:00:00Z","timestamp":1763942400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Nutr Health"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Omega-3 fatty acids are beneficial for health. Omega-3-enriched eggs provide an alternative to enhance dietary omega-3 intake.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the change in EPA (eicosapentaenoic acid), DHA (docosahexaenoic acid) and total omega-3 fatty acids levels in blood after consuming omega-3-enriched eggs in healthy participants and compare with regular eggs and fish oil capsules.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A randomized, open-label, pilot clinical study allocated 43 participants into four groups as follows: Group 1 (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u200910): One omega-3-enriched egg daily, Group 2 (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u200910): Two omega-3-enriched eggs daily, Group 3 (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u200912): One fish oil capsule once daily containing 250\u2005mg EPA\u2009+\u2009DHA, Group 4 (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u200911): One regular (control) egg daily for 30 days. The primary outcome was the change in EPA, DHA, and total omega-3 fatty acid levels in blood plasma on Day 15 and Day 30 compared to baseline.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Consuming one omega-3-enriched egg daily for 30 days increased DHA levels by 63.66%. While fish oil capsules increased plasma DHA level by 91.48%. The highest increase in DHA was in the two omega-3 egg group (92.52%). EPA levels significantly increased (117.46%) in participants consuming two omega-3-enriched eggs daily, which was significantly higher than the fish oil capsule group (111.08%). Total plasma omega-3 levels increased by 97.41% in the two-enriched-egg group, compared to 13.37% in the regular egg group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Omega-3-enriched eggs can be an ideal alternative for individuals who consume eggs but avoid fish\/fish products.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Trial Registration<\/jats:title>\n                    <jats:p>Clinical Trial Registry, India (CTRI Registration number: CTRl\/2020\/02\/023143).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/02601060251399119","type":"journal-article","created":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T19:01:42Z","timestamp":1764010902000},"page":"1783-1792","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["A randomized, open-label, pilot clinical study to evaluate the effect of omega-3-enriched egg supplementation in healthy participants"],"prefix":"10.1177","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7703-6509","authenticated-orcid":false,"given":"Merina","family":"Benny","sequence":"first","affiliation":[{"name":"Arjuna Natural Private Ltd"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7725-8822","authenticated-orcid":false,"given":"Benny","family":"Antony","sequence":"additional","affiliation":[{"name":"Arjuna Natural Private Ltd"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8303-4502","authenticated-orcid":false,"given":"Binu T.","family":"Kuruvilla","sequence":"additional","affiliation":[{"name":"Arjuna Natural Private Ltd"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6787-383X","authenticated-orcid":false,"given":"Giby","family":"Abraham","sequence":"additional","affiliation":[{"name":"Arjuna Natural Private Ltd"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9579-0142","authenticated-orcid":false,"given":"Nishant Kumar","family":"Gupta","sequence":"additional","affiliation":[{"name":"Arjuna Natural Private Ltd"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,11,24]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.21926\/rpn.2501004"},{"key":"e_1_3_3_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.japr.2024.100429"},{"key":"e_1_3_3_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/83.6.1467S"},{"key":"e_1_3_3_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/agriculture12101712"},{"key":"e_1_3_3_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41569-022-00676-y"},{"key":"e_1_3_3_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu13072421"},{"key":"e_1_3_3_8_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.2010.28450D"},{"key":"e_1_3_3_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/134.1.187"},{"key":"e_1_3_3_10_1","first-page":"60","article-title":"Value added eggs seem a good option for improving blood omega-6: Omega-3 ratio and heart health","volume":"6","author":"Khan SA","year":"2017","unstructured":"Khan SA, Hegde M, Wagh U, et al. 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