{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T16:43:12Z","timestamp":1787503392835,"version":"build-2736575974"},"reference-count":13,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T00:00:00Z","timestamp":1768348800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T00:00:00Z","timestamp":1768348800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Nutr Health"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Sibutramine was once a commonly prescribed medication for weight management. However, it was ultimately removed from the market due to its link to serious cardiovascular risks such as stroke and myocardial infarction. While its primary function is to suppress appetite, sibutramine has also been known to trigger a range of psychiatric symptoms, including anxiety, depression, and psychosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To present a case highlighting the potential mental health implications associated with the use of sibutramine.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This article presents a case report; clinical details were documented by the psychiatrist in charge and reviewed by the team. The Naranjo adverse drug reaction Probability Scale was used in this case to evaluate whether the psychotic events were associated with sibutramine use.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>a young female developed severe psychiatric symptoms requiring hospitalization after using sibutramine for weight loss. Treatment included suspending sibutramine and administering Aripiprazole 15\u2005mg.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This case serves as a poignant reminder of the potential dangers associated with using unregulated medications for weight loss purposes and underscores the importance of seeking professional medical guidance when embarking on any kind of treatment regimen.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/02601060251411831","type":"journal-article","created":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T18:55:14Z","timestamp":1768416914000},"page":"397-399","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Weight loss at a cost: A case of sibutramine-induced psychotic disorder"],"prefix":"10.1177","volume":"32","author":[{"given":"Keerthi","family":"Raj","sequence":"first","affiliation":[{"name":"Community Mental Health Service for Working Age, St Mary's Hospital, Leeds, UK"},{"name":"Roseberry Park Hospital, Middlesbrough, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6709-4174","authenticated-orcid":false,"given":"Tsz Yuen","family":"Au","sequence":"additional","affiliation":[{"name":"Newcastle University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanoj","family":"Jacob","sequence":"additional","affiliation":[{"name":"Mental Health Services for Older Adults (MHSOP), Horton Park Medical Centre, Bradford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jatinder","family":"Kour","sequence":"additional","affiliation":[{"name":"Roseberry Park Hospital, Middlesbrough, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,1,14]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.9758\/cpn.2013.11.1.7"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.20344\/amp.14304"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/15563650.2025.2452297"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13098-025-01842-1"},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.3109\/15563650.2010.517208"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/bcp.13420"},{"key":"e_1_3_2_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmedc.2009.01.004"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1590\/1516-4446-2018-0004"},{"issue":"2","key":"e_1_3_2_10_1","first-page":"107","article-title":"Sibutramine-associated psychosis (case report)","volume":"10","author":"Gazdag G","year":"2008","unstructured":"Gazdag G, Szab\u00f3 Z (2008) Sibutramine-associated psychosis (case report). Neuropsychopharmacologia Hungarica: A Magyar Pszichofarmakologiai Egyesulet Lapja = Official Journal of the Hungarian Association of Psychopharmacology 10(2): 107\u2013110.","journal-title":"Neuropsychopharmacologia Hungarica: A Magyar Pszichofarmakologiai Egyesulet Lapja = Official Journal of the Hungarian Association of Psychopharmacology"},{"key":"e_1_3_2_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-789X.2009.00693.x"},{"key":"e_1_3_2_12_1","volume-title":") Adverse Drug Reaction Probability Scale (Naranjo) in Drug Induced Liver Injury","author":"LiverTox: Clinical and Research Information on Drug-Induced Liver Injury","year":"2012","unstructured":"LiverTox: Clinical and Research Information on Drug-Induced Liver Injury (2012) Adverse Drug Reaction Probability Scale (Naranjo) in Drug Induced Liver Injury. Bethesda, MD: National Institute of Diabetes and Digestive and Kidney Diseases. Available at: http:\/\/www.ncbi.nlm.nih.gov\/books\/NBK548069\/ (accessed 27 August 2025)."},{"issue":"3","key":"e_1_3_2_13_1","first-page":"19","article-title":"Obesity: Clinical impact, pathophysiology, complications, and modern innovations in therapeutic strategies","volume":"12","author":"Ullah MI","year":"2025","unstructured":"Ullah MI, Tamanna S (2025) Obesity: Clinical impact, pathophysiology, complications, and modern innovations in therapeutic strategies. Medicines (Basel, Switzerland) 12(3): 19.","journal-title":"Medicines (Basel, Switzerland)"},{"key":"e_1_3_2_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-244X-12-43"}],"container-title":["Nutrition and Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02601060251411831","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/02601060251411831","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02601060251411831","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T17:30:02Z","timestamp":1777656602000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/02601060251411831"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,14]]},"references-count":13,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1177\/02601060251411831"],"URL":"https:\/\/doi.org\/10.1177\/02601060251411831","relation":{},"ISSN":["0260-1060","2047-945X"],"issn-type":[{"value":"0260-1060","type":"print"},{"value":"2047-945X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,14]]}}}