{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T18:02:23Z","timestamp":1777917743079,"version":"3.51.4"},"reference-count":17,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2006,9,1]],"date-time":"2006-09-01T00:00:00Z","timestamp":1157068800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Perfusion"],"published-print":{"date-parts":[[2006,9]]},"abstract":"<jats:p>Introduction: We report two drowning victims with hypothermic circulatory arrest who were resuscitated with the use of extracorporeal circulation (ECC). The first patient developed severe post\u2013bypass pulmonary oedema and inspired us to use a leucocyte\u2013depletion filter in the second patient to attenuate leucocyte\u2013mediated pulmonary reperfusion injury. Methods: In the first patient, a standard extracorporeal circuit was used. In the second patient, systemic leucocyte depletion was applied using leucocyte\u2013depletion filters (Pall RS 1, Pall, Portsmouth, UK), in the venous side of the extracorporeal circuit. Circulating leucocyte counts were measured and arterial blood gas analysis and chest X\u2013rays were performed. Results: Both patients showed a decrease of the circulating leucocyte counts during rewarming and had nearly similar leucocyte counts on arrival at the intensive care unit (ICU). The first patient developed severe pulmonary oedema, with poor arterial blood gases, whereas the second patient, who had leucocyte\u2013depletion by filtration, did not develop severe pulmonary oedema, and had good arterial blood gases. Conclusion: Profound leucocyte\u2013depletion by means of filtration may have contributed to limit leucocyte\u2013mediated pulmonary reperfusion injury.<\/jats:p>","DOI":"10.1177\/0267659106074772","type":"journal-article","created":{"date-parts":[[2007,1,15]],"date-time":"2007-01-15T04:17:44Z","timestamp":1168834664000},"page":"305-308","source":"Crossref","is-referenced-by-count":2,"title":["Leucocyte depletion in a drowning victim during rewarming with extracorporeal                 circulation may limit pulmonary oedema"],"prefix":"10.1177","volume":"21","author":[{"given":"Wytze J","family":"Vermeijden","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans","family":"de Vries","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, University Medical Center Groningen,                         University of Groningen, Groningen, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joke","family":"Kieboom","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, University Medical Center Groningen,                         University of Groningen, Groningen, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tjalling","family":"Waterbolk","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, University Medical Center                         Groningen, University of Groningen, Groningen, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2006,9,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-9572(01)00474-9"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1988.03410030093036"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(00)02307-9"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-199209000-00026"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199711203372103"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(97)70295-2"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1067\/mtc.2000.111050"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(98)01262-4"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(05)80526-8"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1007\/BF01720715"},{"key":"atypb11","first-page":"474","volume":"16","author":"Gonzalez\u2013Rothi RJ","year":"1987","journal-title":"Heart Lung"},{"key":"atypb12","first-page":"IV27","volume":"74","author":"Modell JH","year":"1986","journal-title":"Circulation"},{"key":"atypb13","first-page":"98","volume":"111","author":"Engler RL","year":"1983","journal-title":"Am J Pathol"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1016\/0003-4975(91)90314-G"},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.1999.79.2.609"},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(96)70277-5"},{"key":"atypb17","first-page":"325","volume":"4","author":"Breda MA","year":"1985","journal-title":"J Heart Transplant"}],"container-title":["Perfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0267659106074772","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0267659106074772","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T18:21:53Z","timestamp":1777659713000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0267659106074772"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,9]]},"references-count":17,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2006,9]]}},"alternative-id":["10.1177\/0267659106074772"],"URL":"https:\/\/doi.org\/10.1177\/0267659106074772","relation":{},"ISSN":["0267-6591","1477-111X"],"issn-type":[{"value":"0267-6591","type":"print"},{"value":"1477-111X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,9]]}}}