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The red blood cells of a glucose-6-phosphate dehydrogenase (G6PD)-deficient person are unable to scavenge these free radicals, resulting in haemolysis. Here, we describe the successful anaesthetic management of two G6PD-deficient children who underwent cardiac surgery, on and off CPB, without any obvious haemolytic reaction, followed by a discussion of the disorder, with specific consideration of perioperative management of such cases.<\/jats:p>","DOI":"10.1177\/0267659110380770","type":"journal-article","created":{"date-parts":[[2010,8,12]],"date-time":"2010-08-12T20:26:10Z","timestamp":1281644770000},"page":"417-421","source":"Crossref","is-referenced-by-count":12,"title":["Glucose-6-phosphate dehydrogenase deficiency and cardiac surgery"],"prefix":"10.1177","volume":"25","author":[{"given":"N.","family":"Dogra","sequence":"first","affiliation":[{"name":"Advanced Cardiac Centre, Department of Anaesthesiology and Critical Care, PGIMER, Chandigarh, India,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"GD","family":"Puri","sequence":"additional","affiliation":[{"name":"Advanced Cardiac Centre, Department of Anaesthesiology and Critical Care, PGIMER, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SS","family":"Rana","sequence":"additional","affiliation":[{"name":"Advanced Cardiac Centre, Department of Cardiothoracic and Vascular Surgery, PGIMER, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2010,8,12]]},"reference":[{"key":"atypb1","unstructured":"Glader BE Glucose-6-phosphate dehydrogenase deficiency and related disorders of hexose monophosphate shunt and glutathione metabolism. 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