{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T18:04:05Z","timestamp":1777917845783,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2011,1,12]],"date-time":"2011-01-12T00:00:00Z","timestamp":1294790400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Perfusion"],"published-print":{"date-parts":[[2011,5]]},"abstract":"<jats:p>Emerging technologies and practices for pediatric and neonatal extracorporeal life support (ECLS) are promising. This experiment sought to compare the Medtronic 0800 silicon rubber membrane oxygenator to the Quadrox-iD Pediatric oxygenator in the conventional roller pump circuit, as well as comparing the conventional circuit to an alternative circuit. Three circuits were set up in the experiment. Two conventional roller pump circuits were used to compare the two oxygenators and an alternative circuit consisting of the Quadrox-iD Pediatric oxygenator and Maquet Rotaflow centrifugal pump system was used to identify differences between circuits. All three circuits were primed with Lactated Ringers\u2019 solution and human blood, with an hematocrit of 40%. Testing occurred at flow rates of 250, 500, and 750 ml\/ min at 37\u00b0C for mean arterial line pressures of 60, 80, and 100 mmHg. The results of the experiment showed lower pressure drops and greater retention of total hemodynamic energy (THE) across the Quadrox-iD Pediatric oxygenator compared to the Medtronic 0800 oxygenator. Furthermore, the centrifugal pump used in the alternative circuit showed no back flow at flow rates as low as 250 ml\/min while, on the other hand, rpm levels were kept below 2200 for flow rates as high as 750 ml\/min. Findings support the usage of the Quadrox-iD Pediatric oxygenator in a circuit utilizing the Maquet Rotaflow centrifugal pump system due to lower pressure drops and greater percentage of THE retained across the circuit. Additional advantages of the alternative circuit include rapid set-up time, easy transport, lower priming volumes, and no gravity-dependent venous drainage system so that it can be situated in close proximity to and at the level of the patient.<\/jats:p>","DOI":"10.1177\/0267659110395060","type":"journal-article","created":{"date-parts":[[2011,1,12]],"date-time":"2011-01-12T22:34:16Z","timestamp":1294871656000},"page":"191-198","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":27,"title":["Extracorporeal life support systems: alternative vs. conventional circuits"],"prefix":"10.1177","volume":"26","author":[{"given":"Sameer","family":"Khan","sequence":"first","affiliation":[{"name":"Penn State Hershey Pediatric Cardiovascular Research Center, Department of Pediatrics, Penn State Milton S. Hershey Medical Center, Penn State Hershey College of Medicine, Penn State Hershey Children's Hospital, Hershey, Pennsylvania, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rahul","family":"Vasavada","sequence":"additional","affiliation":[{"name":"Penn State Hershey Pediatric Cardiovascular Research Center, Department of Pediatrics, Penn State Milton S. Hershey Medical Center, Penn State Hershey College of Medicine, Penn State Hershey Children's Hospital, Hershey, Pennsylvania, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Feng Qiu","sequence":"additional","affiliation":[{"name":"Penn State Hershey Pediatric Cardiovascular Research Center, Department of Pediatrics, Penn State Milton S. Hershey Medical Center, Penn State Hershey College of Medicine, Penn State Hershey Children's Hospital, Hershey, Pennsylvania, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allan","family":"Kunselman","sequence":"additional","affiliation":[{"name":"Public Health and Sciences, Penn State Milton S. Hershey Medical Center, Penn State Hershey College of Medicine, Penn State Hershey Children's Hospital, Hershey, Pennsylvania, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akif","family":"\u00dcndar","sequence":"additional","affiliation":[{"name":"Penn State Hershey Pediatric Cardiovascular Research Center, Department of Pediatrics, Penn State Milton S. Hershey Medical Center, Penn State Hershey College of Medicine, Penn State Hershey Childrens Hospital, Hershey, Pennsylvania, USA, Department of Surgery, Penn State Milton S. Hershey Medical Center, Penn State Hershey College of Medicine, Penn State Hershey Children's Hospital, Hershey, Pennsylvania, USA, Department of Bioengineering, Penn State Milton S. Hershey Medical Center, Penn State Hershey..."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2011,1,12]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(00)01562-9"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2010.35"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2009-0696"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1097\/MAT.0b013e318190b6f7"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.2006.04781.x"},{"issue":"1","key":"atypb6","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1177\/0267659108092470","volume":"23","author":"Lawson DS","year":"2008","journal-title":"Perfusion"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1097\/01.mat.0000169111.66328.a8"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1177\/0267659107086270"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1191\/0267659104pf702oa"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2006.05.091"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1051\/ject\/200840166"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1177\/0267659110365366"},{"key":"atypb13","volume-title":"Applied longitudinal analysis","author":"Fitzmaurice GM","year":"2004"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1177\/0267659108097882"},{"key":"atypb15","first-page":"18","volume":"21","author":"Peris A.","year":"2010","journal-title":"Scand J Trauma Resusc Emerg Med"},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1097\/MAT.0b013e318172b445"},{"key":"atypb17","doi-asserted-by":"publisher","DOI":"10.1191\/0267659105pf798cs"},{"key":"atypb18","doi-asserted-by":"publisher","DOI":"10.1097\/MAT.0b013e31818fb9fb"},{"key":"atypb19","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1594.2007.00401.x"},{"key":"atypb20","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1594.2010.01113.x"},{"issue":"11","key":"atypb21","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1111\/j.1525-1594.2010.01127.x","volume":"34","author":"Palanzo D.","year":"2010","journal-title":"Artificial Organs"}],"container-title":["Perfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0267659110395060","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0267659110395060","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T18:24:24Z","timestamp":1777659864000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0267659110395060"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,1,12]]},"references-count":21,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,5]]}},"alternative-id":["10.1177\/0267659110395060"],"URL":"https:\/\/doi.org\/10.1177\/0267659110395060","relation":{},"ISSN":["0267-6591","1477-111X"],"issn-type":[{"value":"0267-6591","type":"print"},{"value":"1477-111X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,1,12]]}}}