{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T17:26:12Z","timestamp":1777915572993,"version":"3.51.4"},"reference-count":17,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2014,4,10]],"date-time":"2014-04-10T00:00:00Z","timestamp":1397088000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Perfusion"],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:sec>\n                    <jats:title>Aims:<\/jats:title>\n                    <jats:p>The aim of present study was to assess whether vitamin D, with proven beneficial effects on the cardiovascular system, has any effect on angina and exercise-induced ischemia in patients with cardiac syndrome X and low serum vitamin D.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Patients with cardiac syndrome X and low serum vitamin D3 were studied before and after treatment with an intramuscular injection of vitamin D3 (300,000 units, every other week for 2 months). We determined the angina episode (per day) and several indices of exercise capacity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>At the end of the treatment course (75\u00b16 day), a significant increase of serum vitamin D3 occurred and was within the normal range (45\u00b18 ng\/ml) and the frequency of angina improved significantly ( p=0.003). Exercise duration and maximal work capacity increased significantly ( p&lt;0.001). Maximal ST-segment depression (mm) decreased significantly ( p=0.001). The calculated Duck treadmill score improved significantly ( p=0.001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Our findings show that vitamin D replacement therapy in patients with cardiac syndrome X and vitamin D deficiency dramatically improves symptoms and signs of ischemia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0267659114526629","type":"journal-article","created":{"date-parts":[[2014,4,10]],"date-time":"2014-04-10T21:59:24Z","timestamp":1397167164000},"page":"60-63","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Vitamin D replacement therapy in patients with cardiac syndrome X"],"prefix":"10.1177","volume":"30","author":[{"given":"A","family":"Andishmand","sequence":"first","affiliation":[{"name":"Cardiovascular Research Center, Afshar Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Z","family":"Ansari","sequence":"additional","affiliation":[{"name":"Cardiovascular Research Center, Afshar Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MH","family":"Soltani","sequence":"additional","affiliation":[{"name":"Cardiovascular Research Center, Afshar Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Mirshamsi","sequence":"additional","affiliation":[{"name":"Cardiovascular Research Center, Afshar Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Raafat","sequence":"additional","affiliation":[{"name":"Cardiovascular Research Center, Afshar Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2014,4,10]]},"reference":[{"key":"bibr1-0267659114526629","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.900191"},{"key":"bibr2-0267659114526629","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(99)00379-4"},{"key":"bibr3-0267659114526629","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.86.6.1864"},{"key":"bibr4-0267659114526629","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(91)90485-4"},{"key":"bibr5-0267659114526629","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.706127"},{"key":"bibr6-0267659114526629","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-5491.2007.02360.x"},{"key":"bibr7-0267659114526629","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2008-1212"},{"key":"bibr8-0267659114526629","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199007053230106"},{"key":"bibr9-0267659114526629","doi-asserted-by":"publisher","DOI":"10.1016\/S0008-6363(02)00327-9"},{"key":"bibr10-0267659114526629","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000100722.34034.E4"},{"key":"bibr11-0267659114526629","doi-asserted-by":"publisher","DOI":"10.1172\/JCI0215219"},{"key":"bibr12-0267659114526629","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.74.6.1141"},{"key":"bibr13-0267659114526629","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000017433.90061.2E"},{"key":"bibr14-0267659114526629","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(02)02664-4"},{"key":"bibr15-0267659114526629","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.74.6.620"},{"key":"bibr16-0267659114526629","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2005.06.046"},{"key":"bibr17-0267659114526629","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsbmb.2009.11.002"}],"container-title":["Perfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0267659114526629","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0267659114526629","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0267659114526629","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T17:24:10Z","timestamp":1777656250000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0267659114526629"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4,10]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["10.1177\/0267659114526629"],"URL":"https:\/\/doi.org\/10.1177\/0267659114526629","relation":{},"ISSN":["0267-6591","1477-111X"],"issn-type":[{"value":"0267-6591","type":"print"},{"value":"1477-111X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,4,10]]}}}