{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T17:26:14Z","timestamp":1777915574192,"version":"3.51.4"},"reference-count":29,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2014,3,21]],"date-time":"2014-03-21T00:00:00Z","timestamp":1395360000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Perfusion"],"published-print":{"date-parts":[[2014,9]]},"abstract":"<jats:p>\n                    Human albumin is the conventional cardiopulmonary bypass circuit primer. However, it has high manufacturing costs. Crystalloid and colloid solutions have been developed as alternatives, including a new generation of non-ionic hydroxyethyl starch (HES). The efficacy of hydroxyethyl starch with a 130 molecular weight and substitution degree of 0.4 (hydroxyethyl starch 130\/0.4) was compared with human albumin for use in cardiopulmonary bypass surgery in American Society of Anesthesiologists\u2019 grade I-II pediatric congenital heart disease patients. Efficacy was evaluated by comparing perioperative hemodynamic parameters, including plasma colloid osmotic pressure, renal function, blood loss, allogeneic blood volumes and plasma volume substitution. The hydroxyethyl starch group exhibited significantly higher preoperative colloid osmotic pressure (p\n                    <jats:italic toggle=\"yes\">&lt;<\/jats:italic>\n                    0.01) and significantly lower operative renal function and postoperative allogeneic blood volumes than the human albumin group. No significant differences were observed in serum creatinine, glucose, hematocrit or lactic acid levels (p&gt;0.05). Our results indicate that hydroxyethyl starch may be a viable alternative to human albumin in pediatric patients undergoing relatively simple cardiopulmonary bypass surgeries.\n                  <\/jats:p>","DOI":"10.1177\/0267659114528267","type":"journal-article","created":{"date-parts":[[2014,3,22]],"date-time":"2014-03-22T01:08:37Z","timestamp":1395450517000},"page":"462-468","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":21,"title":["Comparison of low molecular weight hydroxyethyl starch and human albumin as priming solutions in children undergoing cardiac surgery"],"prefix":"10.1177","volume":"29","author":[{"given":"Na","family":"Miao","sequence":"first","affiliation":[{"name":"Department of Extracorporeal Circulation, Center for Cardiac Intensive Care, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Extracorporeal Circulation, Center for Cardiac Intensive Care, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhongtao","family":"Du","sequence":"additional","affiliation":[{"name":"Department of Extracorporeal Circulation, Center for Cardiac Intensive Care, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Extracorporeal Circulation, Center for Cardiac Intensive Care, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong","family":"Ni","sequence":"additional","affiliation":[{"name":"Department of Extracorporeal Circulation, Center for Cardiac Intensive Care, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jialin","family":"Xing","sequence":"additional","affiliation":[{"name":"Department of Extracorporeal Circulation, Center for Cardiac Intensive Care, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaofang","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Extracorporeal Circulation, Center for Cardiac Intensive Care, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Extracorporeal Circulation, Center for Cardiac Intensive Care, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaotong","family":"Hou","sequence":"additional","affiliation":[{"name":"Department of Extracorporeal Circulation, Center for Cardiac Intensive Care, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2014,3,21]]},"reference":[{"key":"e_1_3_2_2_2","first-page":"24","article-title":"Effect of colloid versus crystalloid administration of cardiopulmonary bypass prime solution on tissue and organ perfusion","volume":"5","author":"Shahbazi S","year":"2011","unstructured":"Shahbazi S, Zeighami A, Allahyary E. Effect of colloid versus crystalloid administration of cardiopulmonary bypass prime solution on tissue and organ perfusion. Iranian Cardiovascular Research Journal 2011; 5: 24\u201331.","journal-title":"Iranian Cardiovascular Research Journal"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1186\/2110-5820-1-2"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1213\/01.ANE.0000061460.59320.B0"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.1995.tb04146.x"},{"key":"e_1_3_2_6_2","first-page":"772","article-title":"Which is the optimal option during pediatric cardiopulmonary bypass: high colloid oncotic pressure priming, ultrafiltration or both?","volume":"40","author":"Liu J","year":"2011","unstructured":"Liu J, Ji B, Long C, . Which is the optimal option during pediatric cardiopulmonary bypass: high colloid oncotic pressure priming, ultrafiltration or both? 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Hemodilution and priming solutions. In: Gravlee GP, Davis RF, Kurusz M, Uttle JR (eds). 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