{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T03:05:36Z","timestamp":1792206336358,"version":"4.4.0"},"reference-count":13,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2015,9,9]],"date-time":"2015-09-09T00:00:00Z","timestamp":1441756800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Perfusion"],"published-print":{"date-parts":[[2016,5]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>We previously described and showed that the method for cardiac de-airing involving: (1) bilateral, induced pulmonary collapse by opening both pleurae and disconnecting the ventilator before cardioplegic arrest and (2) gradual pulmonary perfusion and ventilation after cardioplegic arrest is superior to conventional de-airing methods, including carbon dioxide insufflation of the open mediastinum. This study investigated whether one or both components of this method are responsible for the effective de-airing of the heart.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Twenty patients scheduled for open, left heart surgery were randomized to two de-airing techniques: (1) open pleurae, collapsed lungs and conventional pulmonary perfusion and ventilation; and (2) intact pleurae, expanded lungs and gradual pulmonary perfusion and ventilation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The number of cerebral microemboli measured by transcranial Doppler sonography was lower in patients with open pleurae 9 (6-36) vs 65 (36-210), p=0.004. Residual intra-cardiac air grade I or higher as monitored by transesophageal echocardiography 4-6 minutes after weaning from cardiopulmonary bypass was seen in few patients with open pleurae 0 (0%) vs 7 (70%), p=0.002.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Bilateral, induced pulmonary collapse alone is the key factor for quick and effective de-airing of the heart. Gradual pulmonary perfusion and ventilation, on the other hand, appears to be less important.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0267659115604712","type":"journal-article","created":{"date-parts":[[2015,9,10]],"date-time":"2015-09-10T09:39:33Z","timestamp":1441877973000},"page":"320-326","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Pulmonary collapse alone provides effective de-airing in cardiac surgery: a prospective randomized study"],"prefix":"10.1177","volume":"31","author":[{"given":"Maya","family":"Landenhed","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery, Anesthesia and Intensive Care, Skane University Hospital, Lund University, Lund, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doris","family":"Cunha-Goncalves","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Anesthesia and Intensive Care, Skane University Hospital, Lund University, Lund, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faleh","family":"Al-Rashidi","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Anesthesia and Intensive Care, Skane University Hospital, Lund University, Lund, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leif","family":"Pierre","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Anesthesia and Intensive Care, Skane University Hospital, Lund University, Lund, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"H\u00f6glund","sequence":"additional","affiliation":[{"name":"Clinical Research and Competence Center, Skane University Hospital, Lund University, Lund, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bansi","family":"Koul","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Anesthesia and Intensive Care, Skane University Hospital, Lund University, Lund, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2015,9,9]]},"reference":[{"key":"bibr1-0267659115604712","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2008.10.004"},{"key":"bibr2-0267659115604712","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2009.02.037"},{"key":"bibr3-0267659115604712","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2010.07.013"},{"key":"bibr4-0267659115604712","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2012.11.010"},{"key":"bibr5-0267659115604712","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000022811.46115.70"},{"key":"bibr6-0267659115604712","doi-asserted-by":"publisher","DOI":"10.1111\/aor.12042"},{"key":"bibr7-0267659115604712","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2012.04.010"},{"key":"bibr8-0267659115604712","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(97)00945-4"},{"key":"bibr9-0267659115604712","doi-asserted-by":"publisher","DOI":"10.1136\/thx.22.4.320"},{"key":"bibr10-0267659115604712","doi-asserted-by":"publisher","DOI":"10.1510\/icvts.2007.155523"},{"key":"bibr11-0267659115604712","doi-asserted-by":"publisher","DOI":"10.1016\/0003-4975(95)00577-8"},{"key":"bibr12-0267659115604712","doi-asserted-by":"publisher","DOI":"10.1016\/0003-4975(93)91089-6"},{"key":"bibr13-0267659115604712","first-page":"366","volume":"12","author":"Thomas TV","year":"1971","journal-title":"J Cardiovasc Surg"}],"container-title":["Perfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0267659115604712","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0267659115604712","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0267659115604712","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T17:25:31Z","timestamp":1777656331000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0267659115604712"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9,9]]},"references-count":13,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,5]]}},"alternative-id":["10.1177\/0267659115604712"],"URL":"https:\/\/doi.org\/10.1177\/0267659115604712","relation":{},"ISSN":["0267-6591","1477-111X"],"issn-type":[{"value":"0267-6591","type":"print"},{"value":"1477-111X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,9,9]]}}}