{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T21:42:23Z","timestamp":1781041343531,"version":"3.54.1"},"reference-count":16,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2016,7,20]],"date-time":"2016-07-20T00:00:00Z","timestamp":1468972800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Perfusion"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Minimally invasive coronary artery bypass surgery performed through a left thoracotomy has potential benefits over conventional sternotomy, including reduced surgical trauma, faster recovery and potential improvement in quality of life. This study is a prospective assessment of quality of life in patients undergoing off-pump coronary bypass by median sternotomy and left anterior thoracotomy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Quality of life was assessed by the EuroQoL questionnaire, with additional questions on dyspnoea, angina, wound pain and scar aesthetics. Outcomes were compared across the data sets at pre-operation, three weeks and three months post-operation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Sixty-six (17 minimally invasive and 49 off-pump) patients (mean age 65\u00b112, 7 females and 59 males) were included. Significant differences in mean EuroQol outcomes were observed for activities, F(1,64) = 5.86, (p&lt;0.05), pain scores, F(1,64) = 4.658 (p=0.035) and scar aesthetics, F(1,64) = 16.83 (p&lt;0.05). There was an additional significant interaction, F(1.898, 121.49) = 3.282, (p&lt;0.05), between time and group for activity levels; exploring this further indicated no significant difference at baseline, but significantly greater improvement observed in the minimally invasive group over time. At 3 weeks, 50% of minimally invasive patients compared to 82% of sternotomy patients (p&lt;0.001) required oral analgesia. At 3 months, 8% of minimally invasive patients and 21% of sternotomy patients (p&lt;0.001) required oral analgesia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Off-pump coronary artery bypass performed with a minimally invasive approach through a left thoracotomy appears to result in earlier improvement in quality of life outcomes compared to conventional sternotomy. These results are important when counselling patients regarding the benefits and difference between a left anterior thoractomy MIDCABG and conventional OPCAB and can be used as pilot data for a larger trial examining differences in the MIDCABG and conventional full sternotomy OPCAB procedures.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0267659116657166","type":"journal-article","created":{"date-parts":[[2016,7,20]],"date-time":"2016-07-20T22:23:10Z","timestamp":1469053390000},"page":"50-56","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Comparison of early and late quality of life between left anterior thoracotomy and median sternotomy off-pump coronary artery bypass surgery"],"prefix":"10.1177","volume":"32","author":[{"given":"Julian J.","family":"Nesbitt","sequence":"first","affiliation":[{"name":"Great Western Hospital, Swindon, UK"},{"name":"University of Bristol, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Mori","sequence":"additional","affiliation":[{"name":"Yorkshire and Humber School of Surgery, Yorkshire, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte","family":"Mason-Apps","sequence":"additional","affiliation":[{"name":"University of Bristol, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Asimakopoulos","sequence":"additional","affiliation":[{"name":"University of Bristol, UK"},{"name":"Bristol Heart Institute, Bristol Royal Infirmary, Bristol, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2016,7,20]]},"reference":[{"key":"bibr1-0267659116657166","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(98)00808-X"},{"key":"bibr2-0267659116657166","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(00)01371-0"},{"key":"bibr3-0267659116657166","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezt390"},{"key":"bibr4-0267659116657166","first-page":"290","volume":"4","author":"Diegeler A","year":"1999","journal-title":"Heart Surg Forum"},{"key":"bibr5-0267659116657166","doi-asserted-by":"publisher","DOI":"10.1016\/S1053-0770(05)80013-8"},{"key":"bibr6-0267659116657166","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(00)70176-0"},{"key":"bibr7-0267659116657166","doi-asserted-by":"publisher","DOI":"10.1016\/S1010-7940(97)00216-9"},{"key":"bibr8-0267659116657166","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-6712.1997.tb00435.x"},{"key":"bibr9-0267659116657166","doi-asserted-by":"publisher","DOI":"10.1016\/S1010-7940(97)00199-1"},{"key":"bibr10-0267659116657166","doi-asserted-by":"publisher","DOI":"10.1097\/00019501-199809080-00008"},{"key":"bibr11-0267659116657166","doi-asserted-by":"publisher","DOI":"10.1001\/jama.291.15.1841"},{"key":"bibr12-0267659116657166","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38852.479907.7C"},{"key":"bibr13-0267659116657166","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-005-0911-9"},{"key":"bibr14-0267659116657166","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2008.08.003"},{"key":"bibr15-0267659116657166","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2004.052787"},{"key":"bibr16-0267659116657166","doi-asserted-by":"publisher","DOI":"10.1016\/j.thorsurg.2006.05.006"}],"container-title":["Perfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0267659116657166","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0267659116657166","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0267659116657166","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T17:25:59Z","timestamp":1777656359000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0267659116657166"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7,20]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["10.1177\/0267659116657166"],"URL":"https:\/\/doi.org\/10.1177\/0267659116657166","relation":{},"ISSN":["0267-6591","1477-111X"],"issn-type":[{"value":"0267-6591","type":"print"},{"value":"1477-111X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,7,20]]}}}