{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T17:28:41Z","timestamp":1777915721694,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2019,1,11]],"date-time":"2019-01-11T00:00:00Z","timestamp":1547164800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Perfusion"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>The aim of this study was to evaluate independent risk factors predictive for mortality of patients with Stanford A acute aortic dissection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>From January 2006 to March 2015, a total of 240 consecutive patients diagnosed with acute Stanford A acute aortic dissection underwent surgical aortic repair in our center. After analysis of pre- and perioperative variables, univariate logistic and multivariate logistic regression analyses were performed for mortality of patients. Subsequently, Kaplan\u2013Meier estimation analysis of short- and long-term survival of these variables was carried out.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Primary entry tear in descending aorta (odds ratio\u2009=\u20094.71, p\u2009=\u20090.021), preoperative international normalized ratio higher than 1.2 (odds ratio\u2009=\u20097.36, p\u2009=\u20090.001), additional coronary artery bypass grafting (odds ratio\u2009=\u20093.39, p\u2009=\u20090.003), cannulation in ascending aorta (odds ratio\u2009=\u20093.22, p\u2009=\u20090.005), preoperative neurological coma (odds ratio\u2009=\u20093.30, p\u2009=\u20090.003), and reduced perfusion (odds ratio\u2009=\u20092.91, p\u2009=\u20090.006) as well as prolonged reperfusion time (odds ratio\u2009=\u20093.36, p\u2009=\u20090.002) showed to be independent predictors for early mortality as well as for late mortality (hazard ratio of all variables p\u2009&lt;\u20090.05). Kaplan\u2013Meier survival estimation analysis with up to 9-year-follow-up in terms of these risk factors showed significantly poorer short- and long-term survival (log-rank and Breslow test all p\u2009&lt;\u20090.05).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Our study revealed that early and late mortality of patients with Stanford A acute aortic dissection surgery was significantly influenced by preoperative and perioperative variables as independent predictors especially of variables displaying coronary, cerebral, and visceral malperfusion. Also, short- and long-term survival of patients was significantly poorer in terms of these risk factors.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0267659118822947","type":"journal-article","created":{"date-parts":[[2019,1,11]],"date-time":"2019-01-11T09:45:21Z","timestamp":1547199921000},"page":"375-383","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Factors predictive for early and late mortality after surgical repair for Stanford A acute aortic dissection"],"prefix":"10.1177","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4490-8937","authenticated-orcid":false,"given":"Julia","family":"Merkle","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery, University Hospital Cologne, Cologne, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anton","family":"Sabashnikov","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, University Hospital Cologne, Cologne, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Liebig","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, University Hospital Cologne, Cologne, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8490-5549","authenticated-orcid":false,"given":"Carolyn","family":"Weber","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, University Hospital Cologne, Cologne, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaveh","family":"Eghbalzadeh","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, University Hospital Cologne, Cologne, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oliver","family":"Liakopoulos","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, University Hospital Cologne, Cologne, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Zeriouh","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, University Hospital Cologne, Cologne, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ferdinand","family":"Kuhn-R\u00e9gnier","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, University Hospital Cologne, Cologne, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thorsten","family":"Wahlers","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, University Hospital Cologne, Cologne, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,1,11]]},"reference":[{"key":"bibr1-0267659118822947","unstructured":"Levy D, Le JK. 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