{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T02:12:51Z","timestamp":1779934371432,"version":"3.53.1"},"reference-count":7,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2020,7,15]],"date-time":"2020-07-15T00:00:00Z","timestamp":1594771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Perfusion"],"published-print":{"date-parts":[[2021,4]]},"abstract":"\n Introduction:<\/jats:title>\n We describe a patient who developed severe aortic regurgitation following Impella left ventricular assist device implantation requiring aortic valve replacement.<\/jats:p>\n <\/jats:sec>\n \n Case report:<\/jats:title>\n A previously healthy 34-year-old female presented with chest pain and flu-like symptoms. Electrocardiogram showed widespread ST elevation and serum troponin was raised, consistent with myocarditis. Coronary angiography was normal but the right coronary artery dissected. Subsequent cardiogenic shock required veno-arterial extracorporeal membrane oxygenation and Impella implantation. Myocardial function recovered, but upon removal of the Impella, severe aortic regurgitation was present and she underwent aortic valve replacement, making a full recovery.<\/jats:p>\n <\/jats:sec>\n \n Discussion:<\/jats:title>\n Aortic regurgitation is a rare complication of Impella implantation, and to our knowledge, this is the first reported case successfully treated with aortic valve replacement. Veno-arterial extracorporeal membrane oxygenation and Impella used in tandem are relatively novel, and may add synergistic benefit to strategies for acute cardiogenic shock.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Echocardiography must include frequent assessment of both valvular and myocardial function after Impella removal.<\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/0267659120941339","type":"journal-article","created":{"date-parts":[[2020,7,15]],"date-time":"2020-07-15T04:45:40Z","timestamp":1594788340000},"page":"311-314","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Severe aortic valve regurgitation requiring mechanical aortic valve replacement following Impella device implantation"],"prefix":"10.1177","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2740-2168","authenticated-orcid":false,"given":"Pierre","family":"Vila","sequence":"first","affiliation":[{"name":"Department of Anaesthesia & Intensive Care, Royal Brompton & Harefield NHS Foundation Trust, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felicity","family":"de Vere","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia & Intensive Care, Royal Brompton & Harefield NHS Foundation Trust, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9","family":"Simon","sequence":"additional","affiliation":[{"name":"Department of Transplantation & Mechanical Circulatory Support, Royal Brompton & Harefield NHS Foundation Trust, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Walker","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia & Intensive Care, Royal Brompton & Harefield NHS Foundation Trust, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,7,15]]},"reference":[{"key":"bibr1-0267659120941339","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2015.07.065"},{"key":"bibr2-0267659120941339","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1594.2007.00477.x"},{"key":"bibr3-0267659120941339","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2011.12.025"},{"key":"bibr4-0267659120941339","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2014.06.057"},{"key":"bibr5-0267659120941339","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8191.2012.01454.x"},{"key":"bibr6-0267659120941339","doi-asserted-by":"publisher","DOI":"10.1097\/MAT.0b013e31820e121c"},{"key":"bibr7-0267659120941339","unstructured":"Clinical Trials.gov. Bethesda (MD): National Library of Medicine (US). Identifier NCT03431467. Impella CP with VA ECMO for cardiogenic shock (REVERSE) 2018 Feb 13, https:\/\/clinicaltrials.gov\/ct2\/show\/NCT03431467 (2018, accessed 16 November 2019)."}],"container-title":["Perfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0267659120941339","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0267659120941339","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0267659120941339","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T17:29:25Z","timestamp":1777656565000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0267659120941339"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,15]]},"references-count":7,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["10.1177\/0267659120941339"],"URL":"https:\/\/doi.org\/10.1177\/0267659120941339","relation":{},"ISSN":["0267-6591","1477-111X"],"issn-type":[{"value":"0267-6591","type":"print"},{"value":"1477-111X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,15]]}}}