{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T17:29:52Z","timestamp":1777915792995,"version":"3.51.4"},"reference-count":22,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2020,10,23]],"date-time":"2020-10-23T00:00:00Z","timestamp":1603411200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Perfusion"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>The results of cardiac surgery in patients with end-stage-liver-disease (ESLD) are poor. Concomitant cardiac surgery and orthotopic liver transplantation (OLT) may be an alternative treatment strategy in these patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Between 2001 and 2018, eight patients underwent concomitant cardiac surgery and OLT (Conc_OLT) in our institution. We analyzed their preoperative, intraoperative and postoperative data and compared them to seven high risk patients with ESLD who underwent isolated cardiac surgery (Iso_Surg).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The two groups were not significantly different in terms of gender and age (Conc_OLT: 5 males, 55\u2009\u00b1\u200915\u2009years, Iso_Surg: 4 males, 60\u2009\u00b1\u200910\u2009years). Causes for ESLD were primary biliary cirrhosis (Conc_OLT\u2009=\u20091, Iso_Surg\u2009=\u20091), alcoholism (Conc_OLT\u2009=\u20092, Iso_Surg\u2009=\u20092), viral hepatitis (Conc_OLT\u2009=\u20092, Iso_Surg\u2009=\u20092), cryptogenic (Conc_OLT\u2009=\u20092, Iso_Surg\u2009=\u20091), ischemic (Conc_OLT\u2009=\u20091) and hepatocellular carcinoma (Iso_Surg\u2009=\u20091). Model for End-stage-Liver-Disease (MELD) Score (Conc_OLT\u2009=\u200914, Iso_Surg\u2009=\u200913) and Child-Pugh Score (Conc_OLT\u2009=\u20099.5, Iso_Surg\u2009=\u20098) were not significantly different between the two groups. Median logistic European System for Cardiac Operative Risk Evaluation (EuroSCORE) was 9.5% (Conc_OLT) and 7.1% (Iso_Surg). Cardiac procedures undertaken were aortic valve replacement (Conc_OLT\u2009=\u20096, Iso_Surg\u2009=\u20093), coronary bypass grafting (Conc_OLT\u2009=\u20091,Iso_Surg\u2009=\u20092), tricuspid valve repair (Conc_OLT\u2009=\u20091), combined aortic and mitral valve replacement (Iso_Surg\u2009=\u20091) and excision of atrial myxoma (Iso_Surg\u2009=\u20091). Median length of in-hospital-stay was longer in the Conc_OLT group (73 vs. 42\u2009days; p\u2009=\u20090.11). At 3\u2009months, in-hospital mortality was 25% in the Conc_OLT group (n\u2009=\u20092) and lower compared to 71% observed in the Iso_Surg group (n\u2009=\u20095, p\u2009=\u20090.13).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Concomitant cardiac surgery and OLT is a promising alternative compared to isolated cardiac surgery in high risk patients with ESLD. Given the high operative mortality of cardiac surgery in patients with ESLD, the complex peri-operative management of these patients should be performed in an interdisciplinary team with an expert team of liver specialists involved.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0267659120966549","type":"journal-article","created":{"date-parts":[[2020,10,23]],"date-time":"2020-10-23T08:00:37Z","timestamp":1603440037000},"page":"737-744","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Concomitant cardiac surgery and liver transplantation: an alternative approach in patients with end stage liver failure?"],"prefix":"10.1177","volume":"36","author":[{"given":"Sanjay","family":"Chaubey","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery, Hammermsmith Hospital, London, 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UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jatin","family":"Desai","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, King\u2019s College Hospital, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,10,23]]},"reference":[{"key":"bibr1-0267659120966549","first-page":"60","volume":"5","author":"Kaplan M","year":"2002","journal-title":"Heart Surg 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