{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T00:56:00Z","timestamp":1789088160090,"version":"build-2803163510"},"reference-count":8,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2021,10,8]],"date-time":"2021-10-08T00:00:00Z","timestamp":1633651200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Perfusion"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:p>Lower limb amputation following arterial cannulation for VA-ECMO has been described in the literature. Limb ischemia however following venous cannulation is very rare and not quite understood. We present a case of limb ischemia following venous cannulation. A combination of venous congestion, compartment syndrome and subsequent arterial insufficiency is the proposed pathophysiology. Shock and use of vasopressors are compounding factors. Limb ischemia can be transient and reversible if diagnosed immediately and treated by early removal of the cannula. Our patient was unstable and ECMO dependent, and removal of the cannula was not an option. This resulted in limb loss and eventual above knee amputation. Use of the smallest appropriate venous cannula and early fasciotomy, in addition to hemodynamic optimization are measures that could help in preventing major amputation.<\/jats:p>","DOI":"10.1177\/02676591211050608","type":"journal-article","created":{"date-parts":[[2021,10,9]],"date-time":"2021-10-09T00:38:51Z","timestamp":1633739931000},"page":"414-417","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Lower limb amputation following venous cannulation for VA-ECMO: a case report"],"prefix":"10.1177","volume":"38","author":[{"given":"Natasha","family":"Habr","sequence":"first","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery, Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamal J","family":"Hoballah","sequence":"additional","affiliation":[{"name":"Division of Vascular & Endovascular Surgery, Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamil","family":"Borgi","sequence":"additional","affiliation":[{"name":"Division of Cardiothoracic Surgery, Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Hamadi","sequence":"additional","affiliation":[{"name":"Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Sfeir","sequence":"additional","affiliation":[{"name":"Division of Cardiothoracic Surgery, Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2384-2633","authenticated-orcid":false,"given":"Fady","family":"Haddad","sequence":"additional","affiliation":[{"name":"Division of Vascular & Endovascular Surgery, Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,10,8]]},"reference":[{"key":"bibr1-02676591211050608","doi-asserted-by":"publisher","DOI":"10.1177\/0267659115591622"},{"key":"bibr2-02676591211050608","doi-asserted-by":"publisher","DOI":"10.4103\/0971-9784.197791"},{"key":"bibr3-02676591211050608","doi-asserted-by":"publisher","DOI":"10.1186\/s13613-018-0417-3"},{"key":"bibr4-02676591211050608","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2017.06.81"},{"key":"bibr5-02676591211050608","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2007.09.043"},{"key":"bibr6-02676591211050608","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800830106"},{"key":"bibr7-02676591211050608","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2017.11.094"},{"key":"bibr8-02676591211050608","doi-asserted-by":"publisher","DOI":"10.1055\/s-0037-1608687"}],"container-title":["Perfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02676591211050608","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/02676591211050608","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02676591211050608","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T17:30:57Z","timestamp":1777656657000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/02676591211050608"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,8]]},"references-count":8,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,3]]}},"alternative-id":["10.1177\/02676591211050608"],"URL":"https:\/\/doi.org\/10.1177\/02676591211050608","relation":{},"ISSN":["0267-6591","1477-111X"],"issn-type":[{"value":"0267-6591","type":"print"},{"value":"1477-111X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10,8]]}}}