{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T17:30:50Z","timestamp":1777915850219,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2021,2,26]],"date-time":"2021-02-26T00:00:00Z","timestamp":1614297600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Perfusion"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>The aim of this study was to identify factors associated with primary graft patency 1\u2009year following open lower limb revascularisation (LLR) at a tertiary referral vascular service.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A retrospective analysis of patients undergoing infra-inguinal bypass surgery between January 2016 and May 2017 at a tertiary vascular centre (St Mary\u2019s Hospital, London) was performed. Data regarding patient demographics, comorbidities, type of operation and post-operative anti-thrombotic strategy were collected. Quality of run-off score was assessed from pre-operative imaging.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Seventy-seven cases were included in the analysis. Overall, the primary patency rate at 1-year was 63.6% ( n\u2009=\u200949\/77) and the secondary patency rate was 67.5% ( n\u2009=\u200952\/77). Independent variables with statistically significant inferior patency rates at 1-year were (1) bypasses with below knee targets (p\u2009=\u20090.0096), (2) chronic limb threatening ischaemia indication (p\u2009=\u20090.038), (3) previous ipsilateral revascularisation (p\u2009&lt;\u20090.001) and (4) absence of hypertension history (p\u2009=\u20090.041). There was also a trend towards significance for American Society of Anesthesiologists (ASA) grade (p\u2009=\u20090.06). Independent variables with log-rank test p values of &lt;0.1 were included in a Cox proportional hazards model. The only variable with a statistically significant impact on primary patency rates was previous open or endovascular ipsilateral revascularisation (HR 2.44 (1.04\u20135.7), p\u2009=\u20090.04).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>At 1-year follow-up, previous ipsilateral revascularisation was the most significant factor in affecting patency rates. Patients in this subgroup should therefore be deemed high-risk, which should be reflected in the informed consent and peri-operative management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0267659121995760","type":"journal-article","created":{"date-parts":[[2021,2,27]],"date-time":"2021-02-27T00:56:06Z","timestamp":1614387366000},"page":"276-283","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Factors associated with infrainguinal bypass graft patency at 1-year; a retrospective analysis of a single centre experience"],"prefix":"10.1177","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6362-7535","authenticated-orcid":false,"given":"Pasha","family":"Normahani","sequence":"first","affiliation":[{"name":"Imperial Vascular Unit, Imperial College London NHS Healthcare Trust, London, UK"},{"name":"Department of Surgery and Cancer, Imperial College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ismail Yusuf","family":"Anwar","sequence":"additional","affiliation":[{"name":"Imperial Vascular Unit, Imperial College London NHS Healthcare Trust, London, UK"},{"name":"Department of Surgery and Cancer, Imperial College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alona","family":"Courtney","sequence":"additional","affiliation":[{"name":"Imperial Vascular Unit, Imperial College London NHS Healthcare Trust, London, UK"},{"name":"Department of Surgery and Cancer, Imperial College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amish","family":"Acharya","sequence":"additional","affiliation":[{"name":"Imperial Vascular Unit, Imperial College London NHS Healthcare Trust, London, UK"},{"name":"Department of Surgery and Cancer, Imperial College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Viknesh","family":"Sounderajah","sequence":"additional","affiliation":[{"name":"Imperial Vascular Unit, Imperial College London NHS Healthcare Trust, London, UK"},{"name":"Department of Surgery and Cancer, Imperial College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0524-4384","authenticated-orcid":false,"given":"Chira","family":"Mustafa","sequence":"additional","affiliation":[{"name":"Department of Haematology, Imperial College London NHS Healthcare Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Usman","family":"Jaffer","sequence":"additional","affiliation":[{"name":"Imperial Vascular Unit, Imperial College London NHS Healthcare Trust, London, UK"},{"name":"Department of Surgery and Cancer, Imperial College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Shalhoub","sequence":"additional","affiliation":[{"name":"Imperial Vascular Unit, Imperial College London NHS Healthcare Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Celia","family":"Riga","sequence":"additional","affiliation":[{"name":"Imperial Vascular Unit, Imperial College London NHS Healthcare Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Gibbs","sequence":"additional","affiliation":[{"name":"Imperial Vascular Unit, Imperial College London NHS Healthcare Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Jenkins","sequence":"additional","affiliation":[{"name":"Imperial Vascular Unit, Imperial College London NHS Healthcare Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Colin","family":"Bicknell","sequence":"additional","affiliation":[{"name":"Imperial Vascular Unit, Imperial College London NHS Healthcare Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alun H","family":"Davies","sequence":"additional","affiliation":[{"name":"Imperial Vascular Unit, Imperial College London NHS Healthcare Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Nott","sequence":"additional","affiliation":[{"name":"Imperial Vascular Unit, Imperial College London NHS Healthcare Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher","family":"Aylwin","sequence":"additional","affiliation":[{"name":"Imperial Vascular Unit, Imperial College London NHS Healthcare Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nigel J","family":"Standfield","sequence":"additional","affiliation":[{"name":"Imperial Vascular Unit, Imperial College London NHS Healthcare Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,2,26]]},"reference":[{"key":"bibr1-0267659121995760","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2010.01.073"},{"key":"bibr2-0267659121995760","unstructured":"Health Quality Improvement Partnership. 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