{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T23:24:01Z","timestamp":1789341841184,"version":"build-2803163510"},"reference-count":9,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2022,4,20]],"date-time":"2022-04-20T00:00:00Z","timestamp":1650412800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Perfusion"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:p>A 61-year-old male presented with a history of ischemic cardiomyopathy requiring left ventricular assist device (LVAD) implantation 9\u00a0months prior to presentation. The patient was on aspirin and warfarin as part of his LVAD management. The patient had chest pain and was found to have non-ST elevation myocardial infarction. Despite being on warfarin, a subtherapeutic international normalized ratio of 1.6 was measured on admission. Lactate dehydrogenase was 694 U\/L (12\u2013146) and high-sensitivity troponin peaked at 47,093\u00a0ng\/L. Left heart catheterization revealed an extensive aortic root thrombus (AT). AT is an uncommon cause of thromboembolic events in long-term LVAD patients. Thrombotic events in LVAD patients are pump thrombosis, cerebrovascular accidents, heparin-induced thrombocytopenia, and rarely, AT. There is no well-described management of such a rare complication. In our report, we suggest a multidisciplinary approach and consideration of conservative treatment of these patients.<\/jats:p>","DOI":"10.1177\/02676591221096228","type":"journal-article","created":{"date-parts":[[2022,4,20]],"date-time":"2022-04-20T09:20:38Z","timestamp":1650446438000},"page":"1095-1097","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Aortic root thrombus causing non-ST elevation myocardial infarction after left ventricular assist device"],"prefix":"10.1177","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3164-344X","authenticated-orcid":false,"given":"Akhil S","family":"Kallur","sequence":"first","affiliation":[{"name":"Internal Medicine, MedStar Washington Hospital Center, Washington, D.C., USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fred","family":"Bien-Aime","sequence":"additional","affiliation":[{"name":"Internal Medicine, MedStar Washington Hospital Center, Washington, D.C., USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tariq","family":"Sallam","sequence":"additional","affiliation":[{"name":"Internal Medicine, MedStar Washington Hospital Center, Washington, D.C., USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasir","family":"Jawaid","sequence":"additional","affiliation":[{"name":"Department of Critical Care, MedStar Washington Hospital Center, Washington, D.C., USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3147-5044","authenticated-orcid":false,"given":"Akram M","family":"Zaaqoq","sequence":"additional","affiliation":[{"name":"Internal Medicine, MedStar Washington Hospital Center, Washington, D.C., USA"},{"name":"Department of Critical Care, MedStar Washington Hospital Center, Washington, D.C., USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,4,20]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.04.039"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa012175"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.040246"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-116-1-1"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-116-1-6"},{"issue":"1","key":"e_1_3_3_7_2","first-page":"2","article-title":"Insight into atrial fibrillation in LVAD patients: from clinical implications to prognosis","volume":"8","author":"Sisti N","year":"2020","unstructured":"Sisti N, Mandoli GE, Sciaccaluga C, et al. Insight into atrial fibrillation in LVAD patients: from clinical implications to prognosis. Pulse (Basel, Switzerland) 2020; 8(1\u20132): 2\u201314.","journal-title":"Pulse (Basel, Switzerland)"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.avsg.2020.10.031"},{"key":"e_1_3_3_9_2","first-page":"E63","article-title":"Aortic root and valve thrombosis after implantation of a left ventricular assist device","volume":"23","author":"Freed BH","year":"2011","unstructured":"Freed BH, Jeevanandam V, Jolly N. Aortic root and valve thrombosis after implantation of a left ventricular assist device. J Invasive Cardiol 2011; 23: E63\u2013E65.","journal-title":"J Invasive Cardiol"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2007.11.207"}],"container-title":["Perfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02676591221096228","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/02676591221096228","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02676591221096228","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T17:31:49Z","timestamp":1777656709000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/02676591221096228"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,20]]},"references-count":9,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,7]]}},"alternative-id":["10.1177\/02676591221096228"],"URL":"https:\/\/doi.org\/10.1177\/02676591221096228","relation":{},"ISSN":["0267-6591","1477-111X"],"issn-type":[{"value":"0267-6591","type":"print"},{"value":"1477-111X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,20]]}}}