{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T23:46:30Z","timestamp":1782776790801,"version":"3.54.5"},"reference-count":11,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2023,5,8]],"date-time":"2023-05-08T00:00:00Z","timestamp":1683504000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Perfusion"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Hereditary Angioedema is a rare disease caused by C1 esterase inhibitor deficiency leading to diffuse and potentially life-threatening oedema formation. Preventing attacks is critical, particularly for patients undergoing cardiac surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Report<\/jats:title>\n                    <jats:p>We report a case of a 71-years-old woman with a history of Hereditary Angioedema scheduled for open-heart surgery on Cardiopulmonary Bypass. Multidisciplinar teamwork and patient-targeted strategy were crucial to obtain a favorable outcome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Cardiac surgery is a major stressor for Angioedema attacks because of Complement cascade and inflammatory response activation leading to potential life-threatening oedema formation. In literature only few cases of complex open heart surgery under Cardiopulmonary Bypass are described.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Continuous updating and multidisciplinarity are key elements to manage patients with Hereditary Angioedema in cardiac surgery in order to reduce morbidity and mortality.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/02676591231174773","type":"journal-article","created":{"date-parts":[[2023,5,8]],"date-time":"2023-05-08T23:56:41Z","timestamp":1683590201000},"page":"1017-1019","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Hereditary angioedema in cardiac surgery: Perioperative management considerations for a rare disease"],"prefix":"10.1177","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6930-6302","authenticated-orcid":false,"given":"Enrica Chiara","family":"Adami","sequence":"first","affiliation":[{"name":"Cardiothoracic Intensive Care Unit, Cardiothoracic Department, ASST Spedali Civili di Brescia, Brescia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federica","family":"Magri","sequence":"additional","affiliation":[{"name":"Division of Anesthesiology, Intensive Care and Emergency Medicine, University of Brescia, Brescia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Plotti","sequence":"additional","affiliation":[{"name":"Division of Anesthesiology, Intensive Care and Emergency Medicine, University of Brescia, Brescia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefania","family":"Renzi","sequence":"additional","affiliation":[{"name":"Division of Anesthesiology, Intensive Care and Emergency Medicine, University of Brescia, Brescia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4933-897X","authenticated-orcid":false,"given":"Giovanni","family":"Chiarini","sequence":"additional","affiliation":[{"name":"Division of Anesthesiology, Intensive Care and Emergency Medicine, University of Brescia, Brescia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"De Cicco","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Division, Cardiothoracic Department, ASST Spedali Civili di Brescia, Brescia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,5,8]]},"reference":[{"key":"bibr1-02676591231174773","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2009.10.023"},{"key":"bibr2-02676591231174773","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.161.20.2417"},{"key":"bibr3-02676591231174773","doi-asserted-by":"publisher","DOI":"10.2500\/ar.2015.6.0112"},{"key":"bibr4-02676591231174773","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10092023"},{"key":"bibr5-02676591231174773","doi-asserted-by":"publisher","DOI":"10.1016\/0003-4975(91)90921-C"},{"key":"bibr6-02676591231174773","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2007.09.031"},{"key":"bibr7-02676591231174773","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000004710"},{"key":"bibr8-02676591231174773","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-9-44"},{"key":"bibr9-02676591231174773","doi-asserted-by":"publisher","DOI":"10.1111\/all.13384"},{"key":"bibr10-02676591231174773","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.2012.249"},{"key":"bibr11-02676591231174773","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2013.05.006"}],"container-title":["Perfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02676591231174773","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/02676591231174773","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02676591231174773","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T17:33:16Z","timestamp":1777656796000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/02676591231174773"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,8]]},"references-count":11,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["10.1177\/02676591231174773"],"URL":"https:\/\/doi.org\/10.1177\/02676591231174773","relation":{},"ISSN":["0267-6591","1477-111X"],"issn-type":[{"value":"0267-6591","type":"print"},{"value":"1477-111X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,8]]}}}