{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T17:32:39Z","timestamp":1777915959271,"version":"3.51.4"},"reference-count":16,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2024,2,6]],"date-time":"2024-02-06T00:00:00Z","timestamp":1707177600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"The Construction Fund of Medical Key Disciplines of Hangzhou","award":["Grant: OO20200485"],"award-info":[{"award-number":["Grant: OO20200485"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Perfusion"],"abstract":"<jats:p>Direct percutaneous coronary intervention (PPCI) has significantly reduced cardiac mortality in patients with acute myocardial infarction (AMI), but the mortality rate remains high for those who develop cardiogenic shock (CS), reaching 40% to 50%. Veno-arterial extracorporeal membrane oxygenation (V-A ECMO) provides robust hemodynamic support and oxygen delivery for AMI patients with refractory CS, ensuring adequate organ perfusion and oxygen supply. However, there is currently no standardized optimal Mean Arterial Pressure (MAP) range during V-A ECMO support. Achieving the proper MAP is crucial for adequate myocardial perfusion, cardiac function recovery, successful weaning off of V-A ECMO, and improving long-term outcomes. In this case study, we successfully treated a 55-year-old man with AMI and refractory cardiogenic shock using V-A ECMO. By adjusting ECMO blood flow and employing hemodynamic strategies, including vasoactive drugs, we optimized the MAP, leading to improved cardiac function and successful weaning off of V-A ECMO. This presents a potential opportunity for MAP optimization under ECMO support in patients with acute myocardial infarction and cardiogenic shock.<\/jats:p>","DOI":"10.1177\/02676591241231901","type":"journal-article","created":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T00:12:17Z","timestamp":1707264737000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Preserving flow, saving lives: Successful treatment of aortic valve failure in acute myocardial infarction without flow down-regulation using ECMO - a case report and mini review"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6553-2145","authenticated-orcid":false,"given":"Jing","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Intensive Care Unit, Affiliated Hangzhou First People\u2019s Hospital, Zhejiang University School of Medicine, Hangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao-Kang","family":"Zeng","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Unit, Affiliated Hangzhou First People\u2019s Hospital, Zhejiang University School of Medicine, Hangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Unit, Affiliated Hangzhou First People\u2019s Hospital, Zhejiang University School of Medicine, Hangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-2115-6323","authenticated-orcid":false,"given":"Ying","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Unit, Affiliated Hangzhou First People\u2019s Hospital, Zhejiang University School of Medicine, Hangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,2,6]]},"reference":[{"key":"bibr1-02676591241231901","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.117.005566"},{"key":"bibr2-02676591241231901","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199908263410901"},{"key":"bibr3-02676591241231901","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(67)90023-9"},{"key":"bibr4-02676591241231901","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-016-4536-8"},{"key":"bibr5-02676591241231901","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2021.11.036"},{"key":"bibr6-02676591241231901","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2010.1190"},{"key":"bibr7-02676591241231901","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2021.18323"},{"key":"bibr8-02676591241231901","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.29064"},{"key":"bibr9-02676591241231901","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.0254"},{"key":"bibr10-02676591241231901","doi-asserted-by":"publisher","DOI":"10.1177\/0267659118794112"},{"key":"bibr11-02676591241231901","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2010.08.017"},{"key":"bibr12-02676591241231901","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-021-06506-y"},{"key":"bibr13-02676591241231901","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2020.06.043"},{"issue":"1","key":"bibr14-02676591241231901","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1186\/s13613-015-0094-4","volume":"5","author":"Levy B","year":"2015","journal-title":"Ann Intensive Care"},{"key":"bibr15-02676591241231901","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/eht248"},{"key":"bibr16-02676591241231901","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.11.036"}],"container-title":["Perfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02676591241231901","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/02676591241231901","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02676591241231901","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T17:34:13Z","timestamp":1777656853000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/02676591241231901"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,6]]},"references-count":16,"alternative-id":["10.1177\/02676591241231901"],"URL":"https:\/\/doi.org\/10.1177\/02676591241231901","relation":{},"ISSN":["0267-6591","1477-111X"],"issn-type":[{"value":"0267-6591","type":"print"},{"value":"1477-111X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,6]]},"article-number":"02676591241231901"}}