{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:34:31Z","timestamp":1792787671119,"version":"4.5.0"},"reference-count":24,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2024,8,23]],"date-time":"2024-08-23T00:00:00Z","timestamp":1724371200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Allina Health Foundation"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Perfusion"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Right ventricular dysfunction is associated with mortality in patients with acute respiratory distress syndrome (ARDS) but information in veno-venous extracorporeal membrane oxygenation (ECMO) settings is limited. Study objectives were to examine factors associated with right ventricular (RV) systolic dysfunction (RVSD) and RV dilation in ECMO patients with ARDS, to compare outcomes in those with and without RVSD and RV dilation defined by qualitative and quantitative parameters, and to describe RVSD evolution during ECMO.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective observational study of adult ARDS patients supported with ECMO at a tertiary care hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of a total of 62 patients, 56% had RVSD and 61% had RV dilation by qualitative assessment. Male gender, COVID-19, hypercarbia, and pneumothorax were associated with RVSD and RV dilation. In-hospital mortality was significantly higher in patients with RV dilation vs. no dilation (42% vs. 17%,\n                      <jats:italic>p<\/jats:italic>\n                      = .05) but comparisons for patients with and without RVSD (37% vs. 26%, respectively) did not reach statistical significance. Findings were similar when RV size and function were quantified by right to left ventricle end-diastolic area ratio and fractional area change (39% vs. 21% and 36% vs. 20% respectively; p = NS). Of 39 patients with multiple echocardiograms, 9 of 18 with initially normal RV function developed RVSD while RV function normalized in 10 of 21 patients who began ECMO with RVSD.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Study results suggest an association of RV dilation and RVSD with worse outcomes and a dynamic nature of RV function necessitating close monitoring during the ECMO course.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/02676591241277947","type":"journal-article","created":{"date-parts":[[2024,8,23]],"date-time":"2024-08-23T09:47:17Z","timestamp":1724406437000},"page":"1461-1467","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Predictors and outcomes associated with right ventricular function in patients with acute respiratory distress syndrome treated with Veno-venous extracorporeal membrane oxygenation"],"prefix":"10.1177","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6187-1414","authenticated-orcid":false,"given":"Roman","family":"Melamed","sequence":"first","affiliation":[{"name":"Department of Critical Care, Abbott Northwestern Hospital, Allina Health, Minneapolis, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason","family":"Block","sequence":"additional","affiliation":[{"name":"Department of Critical Care, Abbott Northwestern Hospital, Allina Health, Minneapolis, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4288-0988","authenticated-orcid":false,"given":"Summer L","family":"Martins","sequence":"additional","affiliation":[{"name":"Allina Health, Minneapolis, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-2208-2883","authenticated-orcid":false,"given":"Daniel","family":"Bullard","sequence":"additional","affiliation":[{"name":"Department of Graduate Medical Education, Abbott Northwestern Hospital, Allina Health, Minneapolis, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leeore","family":"Levinstein","sequence":"additional","affiliation":[{"name":"Department of Graduate Medical Education, Abbott Northwestern Hospital, Allina Health, Minneapolis, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Phillips","sequence":"additional","affiliation":[{"name":"Department of Graduate Medical Education, Abbott Northwestern Hospital, Allina Health, Minneapolis, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramiro","family":"Saavedra","sequence":"additional","affiliation":[{"name":"Department of Critical Care, Abbott Northwestern Hospital, Allina Health, Minneapolis, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,8,23]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.21907"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2017.10.75"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-015-4141-2"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-013-2941-9"},{"key":"e_1_3_3_6_2","first-page":"1043","article-title":"Right ventricle dilation as a prognostic factor in refractory acute respiratory distress syndrome requiring veno-venous extracorporeal membrane oxygenation","volume":"82","author":"Lazzeri C","year":"2016","unstructured":"Lazzeri C, Cianchi G, Bonizzoli M, et al. Right ventricle dilation as a prognostic factor in refractory acute respiratory distress syndrome requiring veno-venous extracorporeal membrane oxygenation. Minerva Anestesiol 2016; 82: 1043\u20131049.","journal-title":"Minerva Anestesiol"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/MCC.0000000000000303"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2021.797252"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-021-03591-9"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1177\/0885066619900503"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201408-1404LE"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2020.11.001"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2021.09.036"},{"key":"e_1_3_3_14_2","first-page":"e0268","article-title":"Right ventricular dysfunction and mortality after cannulation for venovenous extracorporeal membrane oxygenation","volume":"2","author":"Ortiz F","year":"2020","unstructured":"Ortiz F, Brunsvold ME, Bartos JA. Right ventricular dysfunction and mortality after cannulation for venovenous extracorporeal membrane oxygenation. Crit Care Explor 2020; 2: e0268.","journal-title":"Crit Care Explor"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jeab067"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/anae.15700"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/MAT.0000000000001854"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2014.10.003"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2019.08.035"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hlc.2017.10.011"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10122535"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hlc.2017.02.006"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1097\/MAT.0000000000001666"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000005751"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-200108000-00009"}],"container-title":["Perfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02676591241277947","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/02676591241277947","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02676591241277947","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T17:35:05Z","timestamp":1777656905000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/02676591241277947"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,23]]},"references-count":24,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["10.1177\/02676591241277947"],"URL":"https:\/\/doi.org\/10.1177\/02676591241277947","relation":{},"ISSN":["0267-6591","1477-111X"],"issn-type":[{"value":"0267-6591","type":"print"},{"value":"1477-111X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,23]]}}}