{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T17:33:24Z","timestamp":1777916004728,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Perfusion"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Despite technological advances, the use of homologous blood to prime the cardiopulmonary bypass (CPB) circuits of infants under 10\u00a0kg remains common. However, such rapid massive transfusion may increase post-CPB morbidity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>We retrospectively included consecutive patients weighing 2.3\u201310\u00a0kg who underwent cardiac surgery under CPB. Patients were divided into two groups based on their priming volumes: low priming volume (LPV) (below the median volume) or high priming volume (HPV) (the median volume or above).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The study included 208 patients, of whom 104 had priming volumes below the median [37.9 (28.4\u201351.7) mL\/kg] and 104 had at least the median volume. We recorded positive correlations between the priming volume, on the one hand, and the peak creatinine and CRP levels within 5\u00a0days postoperatively, the duration of intensive care unit (ICU) stay, and the mechanical ventilation time, on the other. A relationship was also observed between a higher median priming volume and the need for renal replacement therapy in the ICU and mediastinitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Although the differences in priming volume between the twogroups were small, they significantly influenced the postoperative complications. Perfusionists should seek to limit the priming volume to reduce the post-CPB inflammatory response, the duration of ICU stay, and possibly the risk of mediastinitis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/02676591241296319","type":"journal-article","created":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T07:23:32Z","timestamp":1730445812000},"page":"1346-1353","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Reducing the prime cardiopulmonary bypass volume during paediatric cardiac surgery"],"prefix":"10.1177","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3206-7838","authenticated-orcid":false,"given":"Laurent","family":"Mathieu","sequence":"first","affiliation":[{"name":"Department of Pediatric and Congenital Cardiovascular surgery, Haut-L\u00e9v\u00eaque Hospital, Surgical Centre, Bordeaux University Hospital, Pessac, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C\u00e9sar","family":"Brunetti","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Congenital Cardiovascular surgery, Timone Hopital, Aix Marseille University Hospital, Marseille, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean","family":"Detchepare","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Congenital Cardiovascular surgery, Haut-L\u00e9v\u00eaque Hospital, Surgical Centre, Bordeaux University Hospital, Pessac, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maude","family":"Flambard","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Congenital Cardiovascular surgery, Haut-L\u00e9v\u00eaque Hospital, Surgical Centre, Bordeaux University Hospital, Pessac, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Germain","sequence":"additional","affiliation":[{"name":"Research and Innovation Unit in Healthcare and Humanities (URISH), Bordeaux- University Hospital, Bordeaux, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elise","family":"Langouet","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Anesthesia and Critical Care, CHU Bordeaux, Bordeaux, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadir","family":"Tafer","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Anesthesia and Critical Care, CHU Bordeaux, Bordeaux, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fran\u00e7ois","family":"Roubertie","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Congenital Cardiovascular surgery, Haut-L\u00e9v\u00eaque Hospital, Surgical Centre, Bordeaux University Hospital, Pessac, France"},{"name":"IHU Liryc, Electrophysiology and Heart Modeling Institute, Pessac, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7346-7539","authenticated-orcid":false,"given":"Alexandre","family":"Ouattara","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Anesthesia and Critical Care, CHU Bordeaux, Bordeaux, France"},{"name":"Univ. Bordeaux, INSERM, U1034, Biology of Cardiovascular Diseases, Pessac, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,11]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-015-1236-z"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1959-0318(10)70006-3"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(02)04701-X"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2006.02.071"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.127.1.295"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2022.11.037"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/aas.13664"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0039-1700529"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1186\/s43057-022-00084-5"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v27.i12.1161"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/aor.12657"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00068-015-0612-y"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/tme.12481"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12630-022-02319-9"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12288-018-1039-5"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/pan.14637"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2009.08.081"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrtlng.2011.07.012"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD010801"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/vox.13036"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1111\/pan.13368"}],"container-title":["Perfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02676591241296319","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/02676591241296319","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02676591241296319","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T17:35:25Z","timestamp":1777656925000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/02676591241296319"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":21,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["10.1177\/02676591241296319"],"URL":"https:\/\/doi.org\/10.1177\/02676591241296319","relation":{},"ISSN":["0267-6591","1477-111X"],"issn-type":[{"value":"0267-6591","type":"print"},{"value":"1477-111X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11]]}}}