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Refusal of blood transfusions required preoperative optimization and advanced blood conservation strategies. The patient underwent multiple cardiac surgeries and spinal fusion. This case emphasizes multidisciplinary coordination and blood management strategies for surgical cases with religious restrictions.<\/jats:p>","DOI":"10.1177\/02676591251340940","type":"journal-article","created":{"date-parts":[[2025,5,22]],"date-time":"2025-05-22T18:44:09Z","timestamp":1747939449000},"page":"221-224","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Complex cardiac and orthopedic surgery in a 14-year-old with DiGeorge syndrome from a Jehovah\u2019s Witness household: A blood conservation approach"],"prefix":"10.1177","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-8129-6092","authenticated-orcid":false,"given":"Maria E.","family":"Hoyos","sequence":"first","affiliation":[{"name":"Dell Children\u2019s Medical Center and UT Health Austin"},{"name":"Dell Medical School at the University of Texas at Austin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario A.","family":"O\u2019Connor","sequence":"additional","affiliation":[{"name":"Dell Children\u2019s Medical Center and UT Health Austin"},{"name":"Dell Medical School at the University of Texas at Austin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian","family":"Kaufman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cynthia","family":"Keene","sequence":"additional","affiliation":[{"name":"Dell Children\u2019s Medical Center and UT Health Austin"},{"name":"Dell Medical School at the University of Texas at Austin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Madeline","family":"Loftin","sequence":"additional","affiliation":[{"name":"Dell Children\u2019s Medical Center and UT Health Austin"},{"name":"Dell Medical School at the University of Texas at Austin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hugo R.","family":"Martinez","sequence":"additional","affiliation":[{"name":"Dell Children\u2019s Medical Center and UT Health Austin"},{"name":"Dell Medical School at the University of Texas at Austin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr","given":"Charles D.","family":"Fraser","sequence":"additional","affiliation":[{"name":"Dell Children\u2019s Medical Center and UT Health Austin"},{"name":"Dell Medical School at the University of Texas at Austin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erin","family":"Gottlieb","sequence":"additional","affiliation":[{"name":"Dell Children\u2019s Medical Center and UT Health Austin"},{"name":"Dell Medical School at the University of Texas at Austin"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,5,22]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2021.03.033"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/pr.2015.216"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1177\/0267659117747046"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bas.2022.100883"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jspd.2014.03.008"},{"key":"e_1_3_4_7_2","volume-title":"Blood transfusion","author":"National Clinical Guideline Centre (UK)","year":"2015","unstructured":"National Clinical Guideline Centre (UK). 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