{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T16:24:35Z","timestamp":1780676675825,"version":"3.54.1"},"reference-count":6,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Perfusion"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Management of neonatal Group B Streptococcal (GBS) sepsis with multi-organ failure requires innovative approaches when conventional therapies prove insufficient.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Report<\/jats:title>\n                    <jats:p>A term neonate developed severe respiratory failure and septic shock from GBS infection, necessitating veno-arterial extracorporeal membrane oxygenation (V-A ECMO) initiation at 24\u00a0hours of life. During ECMO support, the patient developed hepatic dysfunction with severe hyperbilirubinemia (peak total\/direct bilirubin: 36.9\/31.6\u00a0mg\/dL). A Jafron HA60 hemoadsorption cartridge was integrated into the ECMO circuit, resulting in a 38% bilirubin reduction within 24\u00a0hours. Despite complications including lung atelectasis, renal dysfunction, and nosocomial COVID-19, the patient was successfully decannulated after 15\u00a0days, extubated after 24\u00a0days, and discharged home after 48\u00a0days with normal neurological outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>This case highlights the application of hemoadsorption technology for managing hepatic failure in neonatal ECMO.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Hemoadsorption therapy represents a promising adjunctive treatment for neonates with severe hyperbilirubinemia during ECMO support.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/02676591251366418","type":"journal-article","created":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T06:44:11Z","timestamp":1772433851000},"page":"120-123","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Neonatal hepatic failure for early-onset group B streptococcal sepsis successfully treated using hemoperfusion with Jafron cartridge during V-A ECMO support"],"prefix":"10.1177","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-4118-0832","authenticated-orcid":false,"given":"Elisa","family":"Barberi","sequence":"first","affiliation":[{"name":"Fondazione Monasterio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4240-0099","authenticated-orcid":false,"given":"Giacomo","family":"Bianchi","sequence":"additional","affiliation":[{"name":"Fondazione Monasterio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vitali","family":"Pak","sequence":"additional","affiliation":[{"name":"Fondazione Monasterio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cornel","family":"Marusceac","sequence":"additional","affiliation":[{"name":"Fondazione Monasterio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-6001-832X","authenticated-orcid":false,"given":"Dorela","family":"Haxhiademi","sequence":"additional","affiliation":[{"name":"Fondazione Monasterio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadia","family":"Assanta","sequence":"additional","affiliation":[{"name":"Fondazione Monasterio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Guarino","sequence":"additional","affiliation":[{"name":"Fondazione Monasterio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo Antonio","family":"Del Sarto","sequence":"additional","affiliation":[{"name":"Fondazione Monasterio"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,3,1]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2018.4826"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2004-2275"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2016.00109"},{"key":"e_1_3_4_5_2","first-page":"829","article-title":"Current status of the new generation hemoadsorption cartridges in critical care","volume":"47","author":"Ankawi G","year":"2023","unstructured":"Ankawi G, Xie Y, Yang B, et al. Current status of the new generation hemoadsorption cartridges in critical care. Artif Organs 2023; 47: 829\u2013842.","journal-title":"Artif Organs"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/aor.14457"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1526-0542(04)90053-X"}],"container-title":["Perfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02676591251366418","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/02676591251366418","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02676591251366418","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T17:36:16Z","timestamp":1777656976000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/02676591251366418"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":6,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1177\/02676591251366418"],"URL":"https:\/\/doi.org\/10.1177\/02676591251366418","relation":{},"ISSN":["0267-6591","1477-111X"],"issn-type":[{"value":"0267-6591","type":"print"},{"value":"1477-111X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3]]}}}