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(3) It is the general assumption that any solution other than what is stated in the IFU, may designate an off-label use of that device. But is the use of Normal Saline for washing salvaged blood physiologically the best solution for this autotransfusion process or is it just the way it has always been done and should not be questioned?<\/jats:p>","DOI":"10.1177\/02676591251413495","type":"journal-article","created":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T11:24:10Z","timestamp":1766575450000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["What is the ideal solution for washing salvaged red blood cells using a cell saver for autotransfusion during surgery"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-3732-8635","authenticated-orcid":false,"given":"Gerard J","family":"Myers","sequence":"first","affiliation":[{"name":"Eastern Perfusion International, Dartmouth, NS, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,12,24]]},"reference":[{"issue":"2","key":"e_1_3_3_2_2","first-page":"1","article-title":"Normal saline: past","volume":"106","author":"Liu X","year":"2023","unstructured":"Liu X, Lu M. 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Latta to the secretary of the central board of health, London, affording a view of the rationale and results of his practice in the treatment of cholera by aqueous and saline injections. Int J Epidemiol 2013; 42: 387\u2013390.","journal-title":"Int J Epidemiol"},{"issue":"3","key":"e_1_3_3_6_2","first-page":"78","article-title":"Washing and filtering of cell salvaged blood \u2013 does it make autotransfusion safer? \u2013 transfus altern","volume":"12","author":"Konig G","year":"2012","unstructured":"Konig G, Waters JH. Washing and filtering of cell salvaged blood \u2013 does it make autotransfusion safer? \u2013 transfus altern. Transfus Med 2012; 12(3-4): 78\u201387.","journal-title":"Transfus Med"},{"key":"e_1_3_3_7_2","unstructured":"American Association of Blood Banks. 2007 reference. Standards for perioperative autologous blood collection and administration. 3rd ed. (Addition of Drugs and Solutions).Standard 5.4.4."},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2012.13356"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199905000-00003"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200002000-00055"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aet292"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/aqy036"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1051\/ject\/201850113"},{"key":"e_1_3_3_14_2","first-page":"214","article-title":"In vitro and in vivo comparison of hemoglobin and electrolytes following the collection of cell saver blood washed with either normal saline or plasmalyte A \u2013 j extra corpor","volume":"53","author":"Cholette JM","year":"2021","unstructured":"Cholette JM, McRae BA, Angola R, et al. In vitro and in vivo comparison of hemoglobin and electrolytes following the collection of cell saver blood washed with either normal saline or plasmalyte A \u2013 j extra corpor. 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