{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T11:09:51Z","timestamp":1778238591535,"version":"3.51.4"},"reference-count":4,"publisher":"SAGE Publications","issue":"1_suppl","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Perfusion"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Persistent asystole following restoration of mechanical circulation during extracorporeal cardiopulmonary resuscitation (E-CPR) is typically considered fatal. However, in profound hypothermia, electrical silence may not reflect irreversible myocardial injury.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Report<\/jats:title>\n                    <jats:p>A term neonate with severe meconium aspiration syndrome (MAS) was initially supported on veno-arterial ECMO at a regional hospital and transported to a tertiary ECMO facility. Following decannulation, she suffered cardiac arrest. Mechanical circulation was achieved after prolonged E-CPR with central cannulation, but the patient remained asystolic in the context of profound hypothermia (31.2\u00b0C). Electrical activity reappeared only after controlled rewarming to 33\u00b0C. She was discharged home on day 35 with a good long term neurological outcome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Neonates are particularly prone to rapid hypothermia during resuscitation. Controlled rewarming is essential to determine cardiac viability before establishing futility.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Under profound hypothermia, asystole after restoration of mechanical circulation does not preclude irreversible myocardial damage. Cautious rewarming is mandatory to assess myocardial prognosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/02676591251415350","type":"journal-article","created":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T06:30:36Z","timestamp":1778049036000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Persistent asystole on extracorporeal life support following neonatal E-CPR: Considerations under hypothermia"],"prefix":"10.1177","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-6922-4242","authenticated-orcid":false,"given":"Xabier","family":"Freire-Gomez","sequence":"first","affiliation":[{"name":"Hospital 12 de Octubre"},{"name":"Hospital 12 de Octubre"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enrique","family":"Garcia-Torres","sequence":"additional","affiliation":[{"name":"Hospital 12 de Octubre"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier","family":"Arias-Dachary","sequence":"additional","affiliation":[{"name":"Hospital 12 de Octubre"},{"name":"Hospital 12 de Octubre"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rianseres","family":"Garcia-Benitez","sequence":"additional","affiliation":[{"name":"Hospital 12 de Octubre"},{"name":"Hospital 12 de Octubre"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayte","family":"Garcia-Maellas","sequence":"additional","affiliation":[{"name":"Hospital 12 de Octubre"},{"name":"Hospital 12 de Octubre"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olga","family":"Ordo\u00f1ez-Saez","sequence":"additional","affiliation":[{"name":"Hospital 12 de Octubre"},{"name":"Hospital 12 de Octubre"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luisa","family":"Baron-Gonzalez de Suso","sequence":"additional","affiliation":[{"name":"Hospital 12 de Octubre"},{"name":"Hospital 12 de Octubre"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8651-1500","authenticated-orcid":false,"given":"Imanol","family":"Tajuelo-Llopis","sequence":"additional","affiliation":[{"name":"Hospital 12 de Octubre"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5199-3063","authenticated-orcid":false,"given":"Clara","family":"Aymerich-de Franceschi","sequence":"additional","affiliation":[{"name":"Hospital 12 de Octubre"},{"name":"Hospital 12 de Octubre"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4898-1413","authenticated-orcid":false,"given":"Sylvia","family":"Beld-Hofheinz","sequence":"additional","affiliation":[{"name":"Hospital 12 de Octubre"},{"name":"Hospital 12 de Octubre"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,5,5]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph182111484"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvy305"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1114208"},{"issue":"2","key":"e_1_3_5_5_2","first-page":"151","article-title":"Extracorporeal life support in accidental hypothermia with cardiac arrest: a narrative review","volume":"45","author":"Swol J","year":"2021","unstructured":"Swol J, Darocha T, Paal P, et al. Extracorporeal life support in accidental hypothermia with cardiac arrest: a narrative review. Artif Organs 2021; 45(2): 151\u2013164.","journal-title":"Artif Organs"}],"container-title":["Perfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02676591251415350","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/02676591251415350","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/02676591251415350","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T10:16:58Z","timestamp":1778235418000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/02676591251415350"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":4,"journal-issue":{"issue":"1_suppl","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["10.1177\/02676591251415350"],"URL":"https:\/\/doi.org\/10.1177\/02676591251415350","relation":{},"ISSN":["0267-6591","1477-111X"],"issn-type":[{"value":"0267-6591","type":"print"},{"value":"1477-111X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5]]}}}